Protein Alignment M6 and plp1

DIOPT Version :10

• Sequence 1: NP_001262166.1
• Gene: M6 / 40383
• FlyBaseID: FBgn0037092
• Length: 368
• Species: Drosophila melanogaster
• Sequence 2: XP_012823974.1
• Gene: plp1 / 613099
• XenbaseID: XB-GENE-1008580
• Length: 305
• Species: Xenopus tropicalis
• Alignment Length: 296
• Identity: 72/296 - (24%)
• Similarity: 113/296 - (38%)
• Gaps: 74/296 - (25%)

  Fly   125 CQSCMARIPYATLIATLMCLLGVGIFCFTMYRGASLTVIMVDQVF-----------HLRLIWIEA 178
            |..||..:|:|::|||::|..||.:||...:...|.|..:::..|           |:    |.|
 Frog     7 CVRCMVGVPFASVIATVLCFAGVALFCGCGHEALSGTEKLIETYFSKNYQEYEYLIHV----INA 67

  Fly   179 VQMIFVIIGAGMAALGFMILFVGFLATGATRYKVYRAWRSRV-GGRISCAV-------------- 228
            .|.:...|.......|.::|..||..|.|.::.:.......: ||.||...
 Frog    68 FQYVIYGIAVFFFLFGIILLAEGFYTTTAIKHILGEFKPPAIKGGLISTVTGGPPKGRSPRGRQP 132

  Fly   229 --------------------LMGITYLLNFVWSLILCFLVVVTFIYTMFWNMCTSVEH------- 266
                                |:|:||::..:|.||.....|..:||...|..|.|:..
 Frog   133 VHTIELICRCLGKWLGHPDKLVGVTYVITILWLLIFACAAVPVYIYFNTWVTCQSIAFPGKTTTS 197

  Fly   267 -SQSCIDLTQFHFM----FPPNTKLEDMKVCEKYEIKAFCKDG-VENAEVMFILATLSTLLVLLS 325
             |..|.|...:..:    ||.       |||.. .:.|.||.. .:....:||.|.:.....|::
 Frog   198 VSTLCSDARMYGVLPWNAFPG-------KVCGT-SLLAICKTSEFQMTFHLFIAAFVGAAATLVA 254

  Fly   326 LVHYLMCLSANYAHIRDHEKFQELQEIQNLNELEYS 361
            |:|.|||||||..:   .::..|:.:.|...:.|.|
 Frog   255 LIHALMCLSANRVY---QQRVLEMGKSQETPQAESS 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
M6	NP_001262166.1	Myelin_PLP	122..345	CDD:460144	68/278 (24%)
plp1	XP_012823974.1	Myelin_PLP	4..265	CDD:460144	66/269 (25%)