Protein Alignment M6 and Gpm6b

DIOPT Version :10

• Sequence 1: NP_001262166.1
• Gene: M6 / 40383
• FlyBaseID: FBgn0037092
• Length: 368
• Species: Drosophila melanogaster
• Sequence 2: NP_001171426.1
• Gene: Gpm6b / 14758
• MGIID: 107672
• Length: 328
• Species: Mus musculus
• Alignment Length: 348
• Identity: 85/348 - (24%)
• Similarity: 147/348 - (42%)
• Gaps: 94/348 - (27%)

  Fly    68 PREEILLETNFEDDGGVLTRAYNGNPYNPTIQNRRRNSYRSDHSLDRY----------------- 115
            |..|...|.|.|..                 |.|:.|| |::..:.||
Mouse     3 PAMETAAEENTEQS-----------------QERKVNS-RAEMEIGRYHWMYPGSKNHQYRPVPT 49

  Fly   116 -TERGGE------GECCQSCMARIPYATLIATLMCLLGVGIFCFTMYRGASLTVIMVDQVF---- 169
             .:|.|.      .|||..|:..:|||:|:||::|..||.:||...:...:.||.:::|.|
Mouse    50 LGDRAGPLSSPGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALAGTVAILEQHFSTNT 114

  Fly   170 --HLRLIWIEAVQMIFVIIGAGMAAL----GFMILFVGFLATGATRYKVYRAWRSRVGGRISCAV 228
              |..|  .|.:|::..:| .|:|:.    |.::|..||..|.|.: :::..:::...||....:
Mouse   115 SDHALL--SEVIQLMQYVI-YGIASFFFLYGIILLAEGFYTTSAVK-ELHGEFKTTACGRCISGM 175

  Fly   229 LMGITYLLNFVWSLILCFLVVVTFIYTMFWNMCTSVEHSQS---------CIDLTQFHFM----F 280
            .:.:||:|...|..:..|..|..|::...|:.|..::..||         |:|:.|:..:    |
Mouse   176 FVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSPQSNGTSGVEQICVDVRQYGIIPWNAF 240

  Fly   281 PPNTKLEDMKVCEKYEIKAFCKDGVEN---------AEVMFILATLSTLLVLLSLVHYLMCLSAN 336
            |..                .|...:||         :..:||:|.......:::|:|:||.||:|
Mouse   241 PGK----------------ICGSALENICNTNEFYMSYHLFIVACAGAGATVIALIHFLMILSSN 289

  Fly   337 YAHIRDHEKFQELQEIQNLNELE 359
            :|:::|..|.|..|:|:...|.|
Mouse   290 WAYLKDASKMQAYQDIKAKEEQE 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
M6	NP_001262166.1	Myelin_PLP	122..345	CDD:460144	65/254 (26%)
Gpm6b	NP_001171426.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		7/35 (20%)
		Myelin_PLP	63..298	CDD:460144	65/254 (26%)