Protein Alignment M6 and Gpm6b

DIOPT Version :9

• Sequence 1: NP_001262166.1
• Gene: M6 / 40383
• FlyBaseID: FBgn0037092
• Length: 368
• Species: Drosophila melanogaster
• Sequence 2: NP_001171426.1
• Gene: Gpm6b / 14758
• MGIID: 107672
• Length: 328
• Species: Mus musculus
• Alignment Length: 348
• Identity: 85/348 - (24%)
• Similarity: 147/348 - (42%)
• Gaps: 94/348 - (27%)

  Fly    68 PREEILLETNFEDDGGVLTRAYNGNPYNPTIQNRRRNSYRSDHSLDRY----------------- 115
            |..|...|.|.|..                 |.|:.|| |::..:.||
Mouse     3 PAMETAAEENTEQS-----------------QERKVNS-RAEMEIGRYHWMYPGSKNHQYRPVPT 49

  Fly   116 -TERGGE------GECCQSCMARIPYATLIATLMCLLGVGIFCFTMYRGASLTVIMVDQVF---- 169
             .:|.|.      .|||..|:..:|||:|:||::|..||.:||...:...:.||.:::|.|
Mouse    50 LGDRAGPLSSPGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALAGTVAILEQHFSTNT 114

  Fly   170 --HLRLIWIEAVQMIFVIIGAGMAAL----GFMILFVGFLATGATRYKVYRAWRSRVGGRISCAV 228
              |..|  .|.:|::..:| .|:|:.    |.::|..||..|.|.: :::..:::...||....:
Mouse   115 SDHALL--SEVIQLMQYVI-YGIASFFFLYGIILLAEGFYTTSAVK-ELHGEFKTTACGRCISGM 175

  Fly   229 LMGITYLLNFVWSLILCFLVVVTFIYTMFWNMCTSVEHSQS---------CIDLTQFHFM----F 280
            .:.:||:|...|..:..|..|..|::...|:.|..::..||         |:|:.|:..:    |
Mouse   176 FVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSPQSNGTSGVEQICVDVRQYGIIPWNAF 240

  Fly   281 PPNTKLEDMKVCEKYEIKAFCKDGVEN---------AEVMFILATLSTLLVLLSLVHYLMCLSAN 336
            |..                .|...:||         :..:||:|.......:::|:|:||.||:|
Mouse   241 PGK----------------ICGSALENICNTNEFYMSYHLFIVACAGAGATVIALIHFLMILSSN 289

  Fly   337 YAHIRDHEKFQELQEIQNLNELE 359
            :|:::|..|.|..|:|:...|.|
Mouse   290 WAYLKDASKMQAYQDIKAKEEQE 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
M6	NP_001262166.1	Myelin_PLP	123..345	CDD:279599	65/253 (26%)
Gpm6b	NP_001171426.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		7/35 (20%)
		Myelin_PLP	62..298	CDD:396024	65/255 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832406
Domainoid	1	1.000	107	1.000	Domainoid score	I6511
eggNOG	1	0.900	-	-		E1_KOG4800
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I4803
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D390385at33208
OrthoFinder	1	1.000	-	-		FOG0001336
OrthoInspector	1	1.000	-	-		otm43060
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11683
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5557
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.890