Protein Alignment Est-Q and Ache

DIOPT Version :9

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_038945765.1
• Gene: Ache / 83817
• RGDID: 69313
• Length: 616
• Species: Rattus norvegicus
• Alignment Length: 585
• Identity: 175/585 - (29%)
• Similarity: 264/585 - (45%)
• Gaps: 110/585 - (18%)

  Fly    16 LTAGLTAFLVIFLTGGQGADASETATVTVELYNGQ----------GTVLGNYAYTAWTDRAFMQF 70
            |.:.|...|:..|.||..|:..|...:.|.:..||          |.|              ..|
  Rat    13 LASPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPV--------------SAF 63

  Fly    71 RGIPFAEPPIEELRFRPPVARSPWTGTLNALNFGQRC--------PVITNLDSQMSDAEL-EDCL 126
            .||||||||:...||.||..:.||:|.|:|..|...|        |.....:....:.|| ||||
  Rat    64 LGIPFAEPPVGSRRFMPPEPKRPWSGILDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCL 128

  Fly   127 TLSVYT--KNLSASQPVMFYIYGGGFYNGSS--EDHPPNYLLE-KDVVLVVPQYRVGALGWLS-T 185
            .|:|:|  ...::..||:.:|||||||:|:|  :.:...:|.: :..|||...||||..|:|: .
  Rat   129 YLNVWTPYPRPTSPTPVLIWIYGGGFYSGASSLDVYDGRFLAQVEGTVLVSMNYRVGTFGFLALP 193

  Fly   186 YTEELPGNAPIADILMALDWVQMHISSFGGDPQKVTIFGQSAG-AGVASSLLLSPKTGDNMFKRA 249
            .:.:.|||..:.|..:||.|||.:|::|||||..||:||:||| |.|...:|..|..  ::|.||
  Rat   194 GSRDAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSR--SLFHRA 256

  Fly   250 IVQSGSIFASWAINKDPKAQSRRICIQ--LGC--SGCEQHD-QLVKCIQKAKVIDIL-------- 301
            ::|||:....||.....:|:.|...:.  :||  .|...:| :|:.|::.....|::
  Rat   257 VLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELISCLRTRPAQDLVDHEWHVLP 321

  Fly   302 -KATASESFSPIV-GDLHGILPQQPSELVKSYRRQ-IPILTGFTQHDGSFVLASYYDALAAKVAN 363
             ::....||.|:| ||   .|...|..|:.:...| :.:|.|..:.:||:.|.  |........|
  Rat   322 QESIFRFSFVPVVDGD---FLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLV--YGVPGFSKDN 381

  Fly   364 VSSLSVRQFSQGINDLVNDTSGLTDNILNRLLFKPQALNSHD--H-----SAAVSSYFDLTTNIF 421
            .|.:|..||..|:...|...|.|....:  :|.....|:..|  |     ||.|..:     |:.
  Rat   382 ESLISRAQFLAGVRIGVPQASDLAAEAV--VLHYTDWLHPEDPAHLRDAMSAVVGDH-----NVV 439

  Fly   422 MKSPVITLATKMYTQQRSTPVYVYSFEYE-GTYTRFGYEFGNSHYPFNGGVHHSNDNIYLFATHP 485
              .||..||.::..|  ...||.|.||:. .|.|          :|...||.|..:..::|.. |
  Rat   440 --CPVAQLAGRLAAQ--GARVYAYIFEHRASTLT----------WPLWMGVPHGYEIEFIFGL-P 489

  Fly   486 LEG------QDTQMSQKMVDVWTSFAIEGVPRN--------LSPLSSASGPYNKLN---LEVTKG 533
            |:.      ::...:|:::..||:||..|.|.:        ..|.::|:..|..||   |||.:|
  Rat   490 LDPSLNYTVEERIFAQRLMKYWTNFARTGDPNDPRDSKSPRWPPYTTAAQQYVSLNLKPLEVRRG 554

  Fly   534  533
              Rat   555  554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	167/562 (30%)
		Aes	<137..>240	CDD:223730	46/107 (43%)
Ache	XP_038945765.1	COesterase	37..563	CDD:395084	167/561 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910