Protein Alignment Est-Q and nlgn2a

DIOPT Version :10

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_009301340.1
• Gene: nlgn2a / 556158
• ZFINID: ZDB-GENE-090918-2
• Length: 828
• Species: Danio rerio
• Alignment Length: 512
• Identity: 141/512 - (27%)
• Similarity: 223/512 - (43%)
• Gaps: 100/512 - (19%)

  Fly    69 QFRGIPFAEPPIEELRFRPPVARSPWTGTLNALNFGQRCPVITNLDSQMSDAEL----------- 122
            |:.|:|:|..||.:.||:||.|...|....||..|...||  .|:...:.:..|
Zfish    73 QYLGVPYATAPIGDRRFQPPEAPGSWQEVRNATQFAPVCP--QNVHGVLPEIMLPVWFTDSLDVA 135

  Fly   123 --------EDCLTLSVY--------TKNLSAS---------------QPVMFYIYGGGFYNGSSE 156
                    ||||.|:||        ||....|               :|||.:|:||.:..|:..
Zfish   136 ATYIQNQSEDCLYLNVYVPTEDGPLTKKHDESTLNRPRDEDIRDRRKKPVMLFIHGGSYMEGTGN 200

  Fly   157 DHPPNYLLE-KDVVLVVPQYRVGALGWLSTYTEELPGNAPIADILMALDWVQMHISSFGGDPQKV 220
            ....:.|.. .:|::|...||:|.||:|||..:...||..:.|.:.||.|:..:|..|||||:::
Zfish   201 MFDASVLAAYGNVIVVTMNYRLGVLGFLSTGDQSAKGNYGLLDQIQALRWLNENIGHFGGDPERI 265

  Fly   221 TIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWAINKDPKAQSRRICIQLGCSGCEQH 285
            ||||..|||...:.|:||..: :.:|:|||.||||..:||:|:..|...::.:..::||:..|..
Zfish   266 TIFGSGAGASCVNLLILSHHS-EGLFQRAIAQSGSAISSWSISYQPLKYTKILARKVGCTYGETA 329

  Fly   286 DQLVKCIQKAKV-----IDILKATASESFSPIV-GDLHGILPQQPSELVK-----SYRRQIPILT 339
            | ||.|:::...     .||..|....:|.|:: ||   ::|..|..|::     :|    .:|.
Zfish   330 D-LVDCLRRKNFRELVDQDIQPARYHIAFGPVMDGD---VVPDDPEILMQQGEFLNY----DLLI 386

  Fly   340 GFTQHDGSFVLASYYDALAAKVANVSSLSVRQFSQGINDLVNDTSGL---TDNILNRLLFKPQAL 401
            |..|.:|    ..:.|  .....:...:|...|...|::.|::..|.   .|.:...:.|.....
Zfish   387 GVNQGEG----LKFVD--DGGTESEEGISAAAFDYTISNFVDNLYGYPKGKDILRETIKFMYTDW 445

  Fly   402 NSHDH-SAAVSSYFDLTTNIFMKSPVITLATKMYTQQRSTPVYVYSFEYE-GTYTRFGYEFGNSH 464
            ...|: .....:...|.|:....:|.|..| |::...:| |||.|:|.:. .|.||
Zfish   446 ADRDNGEMRRKTLLALFTDHQWVAPAIATA-KLHADYQS-PVYFYTFYHHCQTETR--------- 499

  Fly   465 YPFNGGVHHSNDNIYLFATHPLEG-----------QDTQMSQKMVDVWTSFAIEGVP 510
             |......|.::..|:|.. |:.|           .|..:|..::..||:||..|.|
Zfish   500 -PEWADAAHGDEIPYVFGV-PMIGATDLFPCNFSKNDIMLSAVVMTYWTNFAKTGDP 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	50..536	CDD:395084	141/512 (28%)
nlgn2a	XP_009301340.1	COesterase	47..608	CDD:395084	141/512 (28%)