Protein Alignment Est-Q and Ces2h

DIOPT Version :9

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 580
• Identity: 154/580 - (26%)
• Similarity: 258/580 - (44%)
• Gaps: 101/580 - (17%)

  Fly     1 MRRRGVYVMLTLCGVLTAGLTAFLVIFLTGGQGADASETATVTVELYNGQGTVLGNYAYTAWTDR 65
            ||...::..||   ..|.||...|.:     ||.|::.....|   :.||  :||:..:....|.
Mouse     1 MRLEQIHARLT---TATCGLLLLLRV-----QGQDSTSPIRTT---HTGQ--ILGSLIHMKDLDV 52

  Fly    66 AFMQFRGIPFAEPPIEELRFRPPVARSPWTGTLNALNFGQRC-PVITNLDSQ------------- 116
            ....|.|||||:||:..|||.||....||.|..:..:....| ..||.::.|
Mouse    53 GVHSFLGIPFAKPPVGPLRFAPPEPPEPWGGVRDGTSHPAMCLQDITAMNMQAFKLLKLTLPPFP 117

  Fly   117 MSDAELEDCLTLSVYTKNLS---ASQPVMFYIYGGGFYNGSSEDHPPNYLLE-KDVVLVVPQYRV 177
            ||    ||||.|::|..:.:   ::.|||.:|:||....|.:..:..:.|.. ::||:|..|||:
Mouse   118 MS----EDCLYLNIYAPDHAHEGSNLPVMVWIHGGSLVIGMASMYDGSMLAAMENVVVVTIQYRL 178

  Fly   178 GALGWLSTYTEELPGNAPIADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASSLLLSPKTG 242
            |.||:.||..|...||....|.:.||.|:|.:|:.|||:|.:|||||.|||....|||::||.:
Mouse   179 GVLGFFSTGDERARGNWGYLDQVAALRWLQQNIAYFGGNPDRVTIFGTSAGGTSVSSLVVSPMS- 242

  Fly   243 DNMFKRAIVQSGSIFASWAINKDPKAQSRRICIQLGCSGCEQHDQ--LVKCIQKAKVIDILKATA 305
            ..:|:.||::||....|..|:.......:.:.   ..|||||.|.  ||.|::.....:|:  ..
Mouse   243 QGLFRGAIMESGVALISSLISVSSDVVYQTVA---NLSGCEQVDSEALVNCLRGKSEEEIM--AI 302

  Fly   306 SESFSPIVGDLHGI-LPQQPSELVKSYR-RQIPILTGFTQHDGSFVLASYYDALAAKVANVSSLS 368
            :::|..|.|.:.|| ||:.|.||:.|.. ..:|.:.|....:..:::.             ||:|
Mouse   303 NKAFKIIPGIVDGIFLPRHPQELMASADFHPVPSIIGVNNDEYGWIIP-------------SSMS 354

  Fly   369 VRQFSQGINDLVNDTSGLTDNILNR-------------LLFKPQALNSHDHSAAVSSYFDLTTNI 420
            :....:|::      ..:...||.|             ||.:....::.|.......:.::..:.
Mouse   355 MIDSKKGMD------RQMVQAILQRRATQMMWPPEVSDLLMEEYMGDNEDPQFLQVQFKEMMKDF 413

  Fly   421 FMKSPVITLATKMYTQQRSTPVYVYSFEYEGTYTRFGYEFGNSHYPFNGGVHHSNDNIYLFATH- 484
            ....|.:.:|   ..|:...||:.|.|::..::      |.:|. |.:....|.::.:::|.:.
Mouse   414 TFVIPALQVA---QFQRSHAPVFFYEFQHRPSF------FKDSK-PSHVKADHGDEILFIFRSFW 468

  Fly   485 -----PLEGQDTQMSQKMVDVWTSFA------IEGVPRNLSPLSSASGPYNKLNLEVTKG 533
                 ....::..:|::|:..|.:||      .||:|  ..|:......|.:|:.:...|
Mouse   469 GGTQVDFTEEEELLSRRMMKYWANFARQRNPNSEGLP--YWPMFDQDEQYLQLDTQPAVG 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	143/542 (26%)
		Aes	<137..>240	CDD:223730	44/103 (43%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:278561	143/543 (26%)
		Aes	<127..>230	CDD:223730	40/102 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810