Protein Alignment Est-Q and Nlg4

DIOPT Version :9

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Alignment Length: 590
• Identity: 140/590 - (23%)
• Similarity: 231/590 - (39%)
• Gaps: 143/590 - (24%)

  Fly    65 RAFMQFRGIPFAEPPIEELRFRPPVARSPWTGTLNALNFGQRCPV-ITNLDSQMS---------- 118
            |:...|.|:|:|.||.::.||.|..|.:||.|...:..:...||. :.|:.::.:
  Fly    65 RSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRL 129

  Fly   119 ----------DAELEDCLTLSVYTK-NLSASQ---PVMFYIYGGGFYNGSSEDHPPNYLLE-KDV 168
                      :.:.||||.|:|::. |..|::   ||:.:|:|..|...|...:..:.|.. .:|
  Fly   130 EYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYGEV 194

  Fly   169 VLVVPQYRVGALGWLST----YTEELPGNAPIADILMALDWVQMHISSFGGDPQKVTIFGQSAGA 229
            |:|...||:|.||:|:.    :......|..:.|.:.||.|:|.:|..|||||..||:.|...||
  Fly   195 VVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGA 259

  Fly   230 GVASSLLLSPKTGDNMFKRAIVQSGSIFASWAINKDPKAQSRRICIQLGCSGCE----QHDQLVK 290
            ...:.|:.||.....:|.|||:.|||.::|||:.:||...:.::..::.|:..:    .|:|:|.
  Fly   260 ACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVD 324

  Fly   291 CIQKAKVIDILKATAS-----ESFSPIVGDL-----HGILPQQPSELVKSYRRQIPILTGFTQH- 344
            |::...:.|:..|...     .||.|.|..:     |..|  ...:|:....|:....:||...
  Fly   325 CLRDVPLEDLYLADIQAPNFLTSFGPSVDGVVIRPGHSNL--DIDDLMARNSRRSSADSGFQSSA 387

  Fly   345 -----------------DGSFVLASYYDALAAKVAN-----------VSSLSVRQFSQGINDLVN 381
                             .||.....|:....|...|           |:..|:.:||  .:|:.|
  Fly   388 GGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFS--AHDIQN 450

  Fly   382 DTSG-LTDNI------------LNRLLF------------KPQALNSHDHSAAVSSYFDLTTNIF 421
            ...| ..|.|            ||.:.:            ....:|:.|.:.|..|.......|.
  Fly   451 GFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIV 515

  Fly   422 MKSPVI---------------------TLATKMYTQQRSTPVYVYSFEYEGTYTRFGYEFGNSHY 465
            ....::                     ..:|...:.|.|...|.|.|:|:   |:.|      .|
  Fly   516 RAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQ---TKDG------DY 571

  Fly   466 PFNGGVHHSNDNIYLFATHPLEG----------QDTQMSQKMVDVWTSFAIEGVPRNLSPLSSAS 520
            |...|..|..|..|:|....::|          .:|.:|:.::..||:||..|.| |......:|
  Fly   572 PQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNP-NEHHRQDSS 635

  Fly   521 GPYNK 525
            .|.:|
  Fly   636 LPVSK 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	140/590 (24%)
		Aes	<137..>240	CDD:223730	36/110 (33%)
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	140/590 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810