Protein Alignment Est-Q and Nlgn3

DIOPT Version :9

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_766520.2
• Gene: Nlgn3 / 245537
• MGIID: 2444609
• Length: 825
• Species: Mus musculus
• Alignment Length: 611
• Identity: 160/611 - (26%)
• Similarity: 248/611 - (40%)
• Gaps: 182/611 - (29%)

  Fly    11 TLCGVLTAGLTAFLVIFLTGGQGADASETATVTVELYNGQ---------GTVLGNYAYTAWTDRA 66
            :||  ||.|   ||.:.|.....|.|.     ||..:.|:         ..:||          .
Mouse    18 SLC--LTLG---FLSLVLRASTQAPAP-----TVNTHFGKLRGARVPLPSEILG----------P 62

  Fly    67 FMQFRGIPFAEPPIEELRFRPPVARSPWTGTLNALNFGQRCPVITNLDSQMSDAEL--------- 122
            ..|:.|:|:|.|||.|.||.||.....|:|..||.:|...||  .|:.:.:.:..|
Mouse    63 VDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCP--QNIHTAVPEVMLPVWFTANLD 125

  Fly   123 ----------EDCLTLSVYT------------KNL-------------SASQPVMFYIYGGGFYN 152
                      ||||.|:||.            ::|             |.::|||.||:||.:..
Mouse   126 IVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYME 190

  Fly   153 GSSEDHPPNYLLE-KDVVLVVPQYRVGALGWLSTYTEELPGNAPIADILMALDWVQMHISSFGGD 216
            |:......:.|.. .:|:::...||||.||:|||..:...||..:.|.:.||.||..:|:.||||
Mouse   191 GTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGD 255

  Fly   217 PQKVTIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWAINKDPKAQSRRICIQLGCSG 281
            |:::|:||...||...|.|.||..: :.:|:|||:||||..:|||:|..|...:..:..::||:.
Mouse   256 PRRITVFGSGIGASCVSLLTLSHHS-EGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNV 319

  Fly   282 CEQHDQLVKCIQK--AKVI---DILKATASESFSPIV-GDLHGILPQQPSELVKSYRRQIPILTG 340
            .:..| :|.|:::  ||.:   ||..|....:|.|:: ||   ::|..|..|::
Mouse   320 LDTVD-MVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGD---VIPDDPEILME----------- 369

  Fly   341 FTQHDGSFVLASYYDALAAKVANVSSLSVRQ-----FSQGINDLVNDTSGLTDNILNRLLFKPQA 400
                .|.|:   .||.:         |.|.|     |.:|:.|..:..||.
Mouse   370 ----QGEFL---NYDIM---------LGVNQGEGLKFVEGVVDPEDGVSGT-------------- 404

  Fly   401 LNSHDHSAAVSSYFDLTTNIF----MKSPVITLATKMYTQ---------QRSTPVYVY------- 445
                |...:||::.|   |::    .|..:......|||.         :|.|.|.::
Mouse   405 ----DFDYSVSNFVD---NLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVE 462

  Fly   446 -SFEYEGTYTRFG---YEFGNSHY------PFNGGVHHSNDNIYLFATHPLEG-----------Q 489
             |......:.|:|   |.:...|:      |......|.::..|:|.. |:.|           .
Mouse   463 PSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGV-PMVGPTDLFPCNFSKN 526

  Fly   490 DTQMSQKMVDVWTSFAIEGVPRNLSP 515
            |..:|..::..||:||..|.|....|
Mouse   527 DVMLSAVVMTYWTNFAKTGDPNKPVP 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	150/583 (26%)
		Aes	<137..>240	CDD:223730	41/103 (40%)
Nlgn3	NP_766520.2	COesterase	39..601	CDD:365897	150/585 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	151..172		1/20 (5%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	622..668

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810