Protein Alignment Est-Q and Ces1a

DIOPT Version :10

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001013786.2
• Gene: Ces1a / 244595
• MGIID: 3648919
• Length: 563
• Species: Mus musculus
• Alignment Length: 502
• Identity: 142/502 - (28%)
• Similarity: 226/502 - (45%)
• Gaps: 65/502 - (12%)

  Fly    50 QGTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELRFRPPVARSPWTGTLNALNFGQRCPVITNLD 114
            ||.|:|.|.....:.:....|.|:|||:||:..|||.||.....|:...|..::...|..||.:.
Mouse    30 QGKVMGKYISLEGSAQPVAVFLGVPFAKPPLGPLRFAPPQPAETWSSVKNTTSYPPMCSQITGVG 94

  Fly   115 SQMSDA---EL--------EDCLTLSVYTKNLSASQ---PVMFYIYGGGFYNGSSEDHPPNYL-L 164
            ..:||.   :|        ||||.|::|:.....|:   |||.:::|||..:|.:.......| .
Mouse    95 PVLSDVFTNQLENVPLEYSEDCLYLNIYSPTDLTSKDRLPVMVWVHGGGLLSGGASTFDGLALST 159

  Fly   165 EKDVVLVVPQYRVGALGWLSTYTEELPGNAPIADILMALDWVQMHISSFGGDPQKVTIFGQSAGA 229
            .::||:||.|||:|..|:|||..|...||....|.:.||.|||.:|::|||||..||:||:|||.
Mouse   160 HENVVIVVIQYRLGIWGFLSTGDEHSRGNWGHLDQVAALQWVQNNIANFGGDPSSVTLFGESAGG 224

  Fly   230 GVASSLLLSPKTGDNMFKRAIVQSGSIFASWAINKDPKAQSRRICIQLGCSGCEQHDQLVKCIQK 294
            ...|.|:|||.| .|:|:|||.:||.........:..:..:.::.|..||......| :|.|:::
Mouse   225 ESVSVLVLSPLT-KNLFQRAISESGVALTPCLFRETTRRAAEQVAIATGCVATTSAD-IVHCLRE 287

  Fly   295 AKVIDILKATASESFSPIVGDLHG----------------ILPQQPSELV--KSYRRQIPILTGF 341
            ....::|..|....|..:  ||.|                :||:.|.|::  ||: ..:|.:.|.
Mouse   288 KTEEELLATTLKMKFFAL--DLLGDPRESYPFLTTVIDGVVLPKAPEEILAEKSF-NTVPYIVGI 349

  Fly   342 TQHD-GSFV-LASYYDALAAKVANVSSLSVRQFSQGINDLVND-TSGLTDNILNRLLFKPQALNS 403
            .:.: |.|: :...|.....|:...|:.|:...|..:.::..: |...|:..|.         .|
Mouse   350 NKQEFGWFIPMMMGYPLSEGKLDQKSATSLLWKSYPLTNISKELTPVATEKYLG---------GS 405

  Fly   404 HDHSAAVSSYFDLTTNIFMKSPVITLATKMYTQQRSTPVYVYSFEYEGTYTRFGYEFGNSHYPFN 468
            .........:.|:..::....|.:.:|  .|.:....|.|:|.|:|..:       |.:...|..
Mouse   406 DCPDKKKDLFLDMMGDVLFAVPSVIVA--RYHRDAGAPTYMYEFKYHPS-------FVSDMRPKT 461

  Fly   469 GGVHHSNDNIYLFATHPL--EG---QDTQMSQKMVDVWTSFAIEGVP 510
            ....| .|.:|.....|.  ||   ::..:|..|:..|.:||..|.|
Mouse   462 VIADH-GDEVYSVWGTPFLKEGASEEEINLSTMMMKFWGNFARNGNP 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	50..536	CDD:395084	142/502 (28%)
Ces1a	NP_001013786.2	COesterase	22..545	CDD:395084	142/502 (28%)