Protein Alignment Est-Q and Cel

DIOPT Version :9

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_058693.2
• Gene: Cel / 24254
• RGDID: 2331
• Length: 612
• Species: Rattus norvegicus
• Alignment Length: 595
• Identity: 175/595 - (29%)
• Similarity: 251/595 - (42%)
• Gaps: 152/595 - (25%)

  Fly    15 VLTAGLTAFLVIFLTGGQGADASETATVTVELYNGQGTVLGNYAYTAWTDRAFMQFRGIPFAEPP 79
            ||..|||..|........||..:|..  .||..|.:.::||..:...        |:|||||...
  Rat     6 VLFLGLTCCLAAACAAKLGAVYTEGG--FVEGVNKKLSLLGGDSVDI--------FKGIPFATAK 60

  Fly    80 IEELRFRPPVARSPWTGTLNALNFGQRC--PVITNLDSQMSDAELEDCLTLSVYT----KNLSAS 138
            ..|...|.|    .|.|||.|.:|.:||  ..||..|:...    ||||.|:::.    |.:|..
  Rat    61 TLENPQRHP----GWQGTLKATDFKKRCLQATITQDDTYGQ----EDCLYLNIWVPQGRKQVSHD 117

  Fly   139 QPVMFYIYGGGFYNGSSE--DHPPNYLLEKD-------VVLVVPQYRVGALGWLSTYTEELPGNA 194
            .|||.:||||.|..||.:  :...|||.:.:       |::|...||||.||:|||....||||.
  Rat   118 LPVMVWIYGGAFLMGSGQGANFLKNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNF 182

  Fly   195 PIADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFAS 259
            .:.|..||:.||:.:|::|||||..:||||:||||...|...||| ....:.:|||.|||...:.
  Rat   183 GLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGAASVSLQTLSP-YNKGLIRRAISQSGVALSP 246

  Fly   260 WAINKDPKAQSRRICIQLGCSGCEQHDQLVKCIQKAKVIDILKATASESFSPIVGDLHGILPQQP 324
            |||.::|...::.|..::||. .|...::..|:   |:.|           |....|...||.:.
  Rat   247 WAIQENPLFWAKTIAKKVGCP-TEDTAKMAGCL---KITD-----------PRALTLAYRLPLKS 296

  Fly   325 SEL-VKSYRRQIPILTGFTQHDGSFV---LASYYDALAAKVANVSSLSVRQFSQGINDLVNDTSG 385
            .|. :..|...||::      ||.|:   ..:.||    ..|::..|:      ||||:
  Rat   297 QEYPIVHYLAFIPVV------DGDFIPDDPINLYD----NAADIDYLA------GINDM------ 339

  Fly   386 LTDNILNRLLFKP------QALNSHDHSAAVSSY------------FDLTTNIFMKSP------- 425
              |..|...:..|      |.:...|....||.:            ||:.|..:.:.|
  Rat   340 --DGHLFATVDVPAIDKAKQDVTEEDFYRLVSGHTVAKGLKGTQATFDIYTESWAQDPSQENMKK 402

  Fly   426 ---------VITLATKMYTQQ-----RSTPVYVYSFEYEGTYTRFGYEFGNSH------YPFNGG 470
                     :..:.|:|...|     :|...|.|.|               ||      ||...|
  Rat   403 TVVAFETDILFLIPTEMALAQHRAHAKSAKTYSYLF---------------SHPSRMPIYPKWMG 452

  Fly   471 VHHSNDNIYL----FATHPL--EGQDTQMSQKMVDVWTSFAIEG--------VPRNLSPLSSASG 521
            ..|::|..|:    ||| ||  ..||..:|:.|:..||:||..|        ||.:..|.::.:|
  Rat   453 ADHADDLQYVFGKPFAT-PLGYRAQDRTVSKAMIAYWTNFAKSGDPNMGNSPVPTHWYPYTTENG 516

  Fly   522 PYNKLNLEVT 531
            .|..:|.::|
  Rat   517 NYLDINKKIT 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	166/571 (29%)
		Aes	<137..>240	CDD:223730	50/111 (45%)
Cel	NP_058693.2	COesterase	26..542	CDD:278561	167/575 (29%)
		Aes	<118..>247	CDD:223730	57/129 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	553..612
		4 X 11 AA tandem repeats, O-glycosylated region	556..599

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810