Protein Alignment Est-Q and cest-1.2

DIOPT Version :9

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_506504.2
• Gene: cest-1.2 / 179914
• WormBaseID: WBGene00011364
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 135/524 - (25%)
• Similarity: 215/524 - (41%)
• Gaps: 126/524 - (24%)

  Fly    23 FLVIFLTGGQGADASETATVTVELYNG--QGTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELRF 85
            |:|:.....|.|.:::     |:|..|  :|..| |..|:.:.:::.:.|.|||:.||||.:|||
 Worm     5 FVVLLWFSAQFAISTK-----VQLSTGIIEGKQL-NSTYSPFGNQSAIAFLGIPYVEPPIGDLRF 63

  Fly    86 RPPVARSPWTGTLNALNFGQRCPVITNLDSQMSDAEL-----EDCLTLSVYT-------KNLSAS 138
            |.|..:..|:|.|....|...|  ::|......:..:     ||||.|:|.|       ||.|
 Worm    64 RKPRPQKTWSGVLETKKFKPAC--MSNSTKTYKNGGIGGPISEDCLYLNVLTNQYCLENKNCS-- 124

  Fly   139 QPVMFYIYGGG--FYNGSSEDHP---PNYL-LEKDVVLVVPQYRVGALGWLSTYTEELPGNAPIA 197
              |:..::|||  |.:.::.:|.   .|:: .::::|:|...||:|..|:......|...|..|.
 Worm   125 --VVIIVHGGGYLFESAATFNHEILVNNFVGQDRNIVVVTINYRLGIFGFGHLNGFEGDKNVGIF 187

  Fly   198 DILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWAI 262
            |.|.|:.||:..|..|||:..::|:.|.||||||.::..:||.| ..:..:.||.||.:     .
 Worm   188 DTLEAVKWVRREIKQFGGNKDRITLAGHSAGAGVVAAFTISPLT-KGLIHQQIVMSGPM-----T 246

  Fly   263 NKDPKAQSRRICIQLGCSGCE----------QH--DQLVKCIQKAKVIDILKA----TASESF-- 309
            |...|:..:.:.......||.          :|  :|:..|::|....::|.|    ..:.:|
 Worm   247 NMSKKSNFKGMTAMAERVGCHSKKYGFNKLPEHEVEQVYSCLRKKPAQELLDAQLWLLQNSTFYF 311

  Fly   310 --SPIVGDLHGILPQQPSELVKSYRRQ----IPILTGFTQ---HDGSFVLASYYDALAAKVANVS 365
              .|:.|:   .:...|..|   |..:    |..|.|.|.   .|..::..|.|.....|...:.
 Worm   312 GAPPVDGE---FITDYPDNL---YSEKSIFSINTLLGTTTRELQDTGYISNSNYSKFETKETFLK 370

  Fly   366 SL----------SVRQFSQG-----INDLVNDTSGLTDNILNRLLFKPQALNSHDHSAAVSSYFD 415
            :|          ....||..     ||.  :|:..|:|:    :.|..||:|..|..|
 Worm   371 NLCDQIGIEIYKESEDFSSKCQKWYING--SDSKSLSDD----MEFYTQAINLADAHA------- 422

  Fly   416 LTTNIFMKSPVITLATKMYTQQRSTPVYVYSFEYEGTYTRFGYEFGNSHYPFNGGVHHSNDNIYL 480
                                 ::...||:||:.|.|....|      ..|......|||.|.||.
 Worm   423 ---------------------RKGKKVYMYSYAYSGAGPAF------KKYMKVKSPHHSEDLIYT 460

  Fly   481 FATH 484
            |.||
 Worm   461 FGTH 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	131/508 (26%)
		Aes	<137..>240	CDD:223730	34/108 (31%)
cest-1.2	NP_506504.2	COesterase	21..536	CDD:278561	131/503 (26%)
		Aes	<125..>250	CDD:223730	41/130 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810