Protein Alignment Est-Q and cest-24

DIOPT Version :10

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_504613.1
• Gene: cest-24 / 179017
• WormBaseID: WBGene00020891
• Length: 658
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 155/542 - (28%)
• Similarity: 239/542 - (44%)
• Gaps: 104/542 - (19%)

  Fly    37 SETATVTVELYNGQGTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELRFRPPVARSPWTGTLNAL 101
            ||.|.|.|:    ||.:.|....||..|...: |.|||:||||:.||||:.|.....|.|.....
 Worm    93 SENAIVRVQ----QGLLEGFRVKTAKGDLCDV-FHGIPYAEPPVGELRFQKPQPPKAWEGIRKCN 152

  Fly   102 NFGQRCPVITNLDSQM-------SDAELEDCLTLSVYTKNLSASQ--PVMFYIYGGGFYNGSSED 157
            .:..|     ::..:|       |..:.||||.|:|:...:...:  ||:|||:|||:...|:|.
 Worm   153 KYPNR-----SIHKEMPWDKALPSANQSEDCLYLNVFAPKIREDKKYPVLFYIHGGGYVMDSAER 212

  Fly   158 HPP----NYLLEKDVVLVVPQYRVGALGWLSTYTEELPGNAPIADILMALDWVQMHISSFGGDPQ 218
            :..    ..|:.:::::|...||:|.||:|||..:..|||..:.|:|.|:.||..:||||||||:
 Worm   213 YTAKNICKLLVSREIIVVTFHYRLGFLGFLSTGDDVCPGNYGLFDMLEAMRWVHANISSFGGDPE 277

  Fly   219 KVTIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWAI--NKDPKAQSRRICIQLGCSG 281
            .:|:.||||||..|..|..||.| ..:|||.||..|:.:..||.  |.|.:...::...:||..
 Worm   278 NITLSGQSAGAAAADLLSFSPLT-KGLFKRKIVMGGNSYCHWATTSNHDIREYCKKWAKRLGWK- 340

  Fly   282 CEQHDQLVKCIQKAKVIDIL---------KATASESFS---------PIVGDLHG-ILPQQPSEL 327
                .||....::.:.:||.         |...:..||         |:...:.| |||.. .::
 Worm   341 ----PQLNYANKREESVDIFNFFNGLPTSKLGMTMFFSNTIFKECQLPLAPVIDGEILPHD-LKV 400

  Fly   328 VKSYRRQIPILTGFTQHDGSFVLA------------SYYDALAAKVANVSSLSVRQFSQGINDLV 380
            ::..:..:|.|.|..:::.....|            |..|.|:.|    :.||..:.......:.
 Worm   401 LRETQEHVPSLVGGGEYEALLFCAIGLLRGTEKEINSAIDVLSRK----NRLSRSKIEAMTEKVY 461

  Fly   381 NDTSGLTDNILNRLLFKPQALNSHDHSAAVSSYFDLTTNIFMKSPVITLATKMYTQQRSTPVYVY 445
            .|:..|..:...|.:|..|.::  |..|...:|      .||:.          .|||....|.|
 Worm   462 GDSPALRADSKARKMFFVQLIS--DIFANYGNY------RFMRD----------CQQRGVECYGY 508

  Fly   446 SFEYEGTYTRFGYEFGNSH-YPFNGGVHHSN-----DNIYLFATHPLEGQDTQMSQKMVDVWTSF 504
            ||::: :...:|:   ..| .||.||.|.|.     |..|:.|...:...|..:|....|.:|:|
 Worm   509 SFDHQ-SKQMWGW---LQHVVPFTGGTHTSELSYLFDCNYMSAPLGMNKTDKVVSGMTADYFTNF 569

  Fly   505 AIEGVPRNLSPLSSASGPYNKL 526
            ...|.|         :||.::|
 Worm   570 VKFGTP---------NGPNSQL 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	50..536	CDD:395084	150/529 (28%)
cest-24	NP_504613.1	COesterase	97..608	CDD:395084	152/538 (28%)