Protein Alignment Est-Q and cest-10

DIOPT Version :9

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_501133.3
• Gene: cest-10 / 177493
• WormBaseID: WBGene00016595
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 119/544 - (21%)
• Similarity: 216/544 - (39%)
• Gaps: 134/544 - (24%)

  Fly    41 TVTVELYNGQ--GTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELRFRPPVARSPWTGTLNALNF 103
            :|.||...|:  |..:||          |..|:.||||:||:.:|||:.|.....|.|..||.::
 Worm    21 SVIVETSLGKLNGDQIGN----------FHLFKKIPFAKPPLGKLRFQKPQPAETWNGVRNAKDY 75

  Fly   104 GQRCPVITNLDSQMSDAELEDCLTLSVYTKNL---SASQPVMFYIYGGGFYNGSSEDHPPNYLL- 164
            |..|...::....:.....||||.|:::|...   |.:..|:.|::||..:..|:......:||
 Worm    76 GPACMSNSSTTKTVQKWVDEDCLHLNIFTSETCLKSKNCAVVIYLHGGNLHYDSAVMFNDTFLLH 140

  Fly   165 ---EKDVVLVVPQYRVGALGWLSTYTEEL-PGNAPIADILMALDWVQMHISSFGGDPQKVTIFGQ 225
               .:::|.|:|..|:|.........:.: |.|..:.|:|.|:::.:..|.:|||:.::.|:.|.
 Worm   141 TYASQEIVFVIPAVRLGIFSHFVVEDQSIAPNNLALFDMLQAMEFAKSDIHNFGGNNKRTTLLGH 205

  Fly   226 SAGAGVASSLLLSPK--TGDNMFKRAIVQSGSI--------------FASWA--INKDPKAQSRR 272
            |.|..|||.|..|.|  |..::|::.|..|...              ||..|  :.|:.|...:.
 Worm   206 SYGGTVASMLSFSTKVNTDLSLFQQYISMSSPTNFDTLELQVERTYRFAEHANCLPKNSKFMRKN 270

  Fly   273 ICIQLGCSGCEQHDQLVKCIQKAKVIDILKATAS--ESFSPIVGD--LHGILPQQPSELVKSYR- 332
                      ::...:..|::|....::|:...|  |:..|:.|.  :.|.:.|:..|  :.:.
 Worm   271 ----------QKEVYMRDCLKKKSASELLRIQRSLEEAGYPVYGGSVMRGPIFQEVLE--RDFMD 323

  Fly   333 --RQIPILTGFTQHDGSFVLASY-----------YDALAAKVANVSSLSVRQFSQGINDLVNDTS 384
              ..|..|||.|::: |.|...|           |:.:..|..:.|.....:|
 Worm   324 SPNNITSLTGCTKYE-SLVYDHYRNMGKALGFENYEEVNEKYRSDSKEGKIEF------------ 375

  Fly   385 GLTDNILNRLLFKPQALNSHDHSAAVSSYFDLTTNIFMKSPVITLATKM-YTQQRSTPVYVYSFE 448
               ||:.|                        .|.|.:    |.:.|:: ...:::.|.|.|.:.
 Worm   376 ---DNVKN------------------------ATQIML----IQIRTRVNKILKKNIPAYHYEYA 409

  Fly   449 YEGTYTRFGYEFGNSHYPFNGGVHHSNDNIYLFATHPL--EGQDTQMSQKMVDVWTSFAIEGVPR 511
            |.            .|      .:|::|..::...||.  :..:.::......::.:|...|.|.
 Worm   410 YP------------KH------ANHTDDLFFIMGVHPFIQDENEIKLGNFYRSMFLNFIKTGNPG 456

  Fly   512 NLSPLSSASG-PYNKLNLEVTKGD 534
            |....::.:| .|.::|...|.|:
 Worm   457 NGCDGANLNGSTYFEVNWNETTGE 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	119/544 (22%)
		Aes	<137..>240	CDD:223730	30/107 (28%)
cest-10	NP_501133.3	Abhydrolase	23..503	CDD:389770	118/542 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810