Protein Alignment Est-Q and cest-10

DIOPT Version :10

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_501133.3
• Gene: cest-10 / 177493
• WormBaseID: WBGene00016595
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 119/544 - (21%)
• Similarity: 216/544 - (39%)
• Gaps: 134/544 - (24%)

  Fly    41 TVTVELYNGQ--GTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELRFRPPVARSPWTGTLNALNF 103
            :|.||...|:  |..:||          |..|:.||||:||:.:|||:.|.....|.|..||.::
 Worm    21 SVIVETSLGKLNGDQIGN----------FHLFKKIPFAKPPLGKLRFQKPQPAETWNGVRNAKDY 75

  Fly   104 GQRCPVITNLDSQMSDAELEDCLTLSVYTKNL---SASQPVMFYIYGGGFYNGSSEDHPPNYLL- 164
            |..|...::....:.....||||.|:::|...   |.:..|:.|::||..:..|:......:||
 Worm    76 GPACMSNSSTTKTVQKWVDEDCLHLNIFTSETCLKSKNCAVVIYLHGGNLHYDSAVMFNDTFLLH 140

  Fly   165 ---EKDVVLVVPQYRVGALGWLSTYTEEL-PGNAPIADILMALDWVQMHISSFGGDPQKVTIFGQ 225
               .:::|.|:|..|:|.........:.: |.|..:.|:|.|:::.:..|.:|||:.::.|:.|.
 Worm   141 TYASQEIVFVIPAVRLGIFSHFVVEDQSIAPNNLALFDMLQAMEFAKSDIHNFGGNNKRTTLLGH 205

  Fly   226 SAGAGVASSLLLSPK--TGDNMFKRAIVQSGSI--------------FASWA--INKDPKAQSRR 272
            |.|..|||.|..|.|  |..::|::.|..|...              ||..|  :.|:.|...:.
 Worm   206 SYGGTVASMLSFSTKVNTDLSLFQQYISMSSPTNFDTLELQVERTYRFAEHANCLPKNSKFMRKN 270

  Fly   273 ICIQLGCSGCEQHDQLVKCIQKAKVIDILKATAS--ESFSPIVGD--LHGILPQQPSELVKSYR- 332
                      ::...:..|::|....::|:...|  |:..|:.|.  :.|.:.|:..|  :.:.
 Worm   271 ----------QKEVYMRDCLKKKSASELLRIQRSLEEAGYPVYGGSVMRGPIFQEVLE--RDFMD 323

  Fly   333 --RQIPILTGFTQHDGSFVLASY-----------YDALAAKVANVSSLSVRQFSQGINDLVNDTS 384
              ..|..|||.|::: |.|...|           |:.:..|..:.|.....:|
 Worm   324 SPNNITSLTGCTKYE-SLVYDHYRNMGKALGFENYEEVNEKYRSDSKEGKIEF------------ 375

  Fly   385 GLTDNILNRLLFKPQALNSHDHSAAVSSYFDLTTNIFMKSPVITLATKM-YTQQRSTPVYVYSFE 448
               ||:.|                        .|.|.:    |.:.|:: ...:::.|.|.|.:.
 Worm   376 ---DNVKN------------------------ATQIML----IQIRTRVNKILKKNIPAYHYEYA 409

  Fly   449 YEGTYTRFGYEFGNSHYPFNGGVHHSNDNIYLFATHPL--EGQDTQMSQKMVDVWTSFAIEGVPR 511
            |.            .|      .:|::|..::...||.  :..:.::......::.:|...|.|.
 Worm   410 YP------------KH------ANHTDDLFFIMGVHPFIQDENEIKLGNFYRSMFLNFIKTGNPG 456

  Fly   512 NLSPLSSASG-PYNKLNLEVTKGD 534
            |....::.:| .|.::|...|.|:
 Worm   457 NGCDGANLNGSTYFEVNWNETTGE 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	50..536	CDD:395084	115/535 (21%)
cest-10	NP_501133.3	alpha/beta hydrolases	20..503	CDD:473884	119/544 (22%)