Protein Alignment Est-Q and cest-5.1

DIOPT Version :10

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_501022.3
• Gene: cest-5.1 / 177429
• WormBaseID: WBGene00015279
• Length: 580
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 130/524 - (24%)
• Similarity: 225/524 - (42%)
• Gaps: 106/524 - (20%)

  Fly    20 LTAFLVIFLTGGQGADASETATVTVELYNGQGTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELR 84
            |...|:||:     .:|:::..:.....:.:|..:|:|..          |:.||||:||:..||
 Worm     4 LRLLLLIFI-----INAADSLIIHTSFGHLEGAEIGDYHL----------FKKIPFAKPPVGNLR 53

  Fly    85 FRPPVARSPWTGTLNALNFGQRCPVITNLDSQMSDAEL--EDCLTLSVYTKN---LSASQPVMFY 144
            |:.|.|...|.|..:|:.:|..|  ::|.....|..:.  ||||.::::|..   .|.:..:..|
 Worm    54 FQKPEAAGKWDGIRSAIEYGPAC--MSNSSKTKSPQKWVDEDCLHVNIFTSKKCLKSRNCAIAVY 116

  Fly   145 IYGGGFYNGSSEDHPPNYLLE----KDVVLVVPQYRVGALGWLSTYTEEL-PGNAPIADILMALD 204
            |:|||....|:.......||:    :||:||:|.:|:|.....:.:.:.: |.|..:.||.:||:
 Worm   117 IHGGGLTYDSAVMFNDTVLLDTFVKRDVILVIPGFRLGIFSHFTVHNQNVAPNNLALYDITLALE 181

  Fly   205 WVQMHISSFGGDPQKVTIFGQSAGAGVASSLLLSPKTGD--NMFKRAIVQSGSIFASWAINKDPK 267
            :|:..|.||||:.||:|:||.|.|.|:||.:..|.:...  ::|::|||.||..:  :...||..
 Worm   182 FVKSEIHSFGGNSQKITLFGHSYGGGLASMMTFSSEINRDLSLFQQAIVMSGGFY--FEELKDHI 244

  Fly   268 AQSRRICIQLGCS----------GCEQHDQLVKCIQKAKVIDILK--ATASESFSPIVGDLHGIL 320
            ..::|......||          ..:|...::||:||...:::|:  ....:...|   |..|::
 Worm   245 EGTKRFVEYANCSVPLKLERKMERSQQEMYMMKCLQKLSGMELLRIQRLLEDKGYP---DFGGVI 306

  Fly   321 PQQP-------SELVKSYRRQIPILTGFTQHDGSFVLASYYDALAAKVANVSSLSVRQFSQGIND 378
            .::|       .||:|| .:.||:|||.|..:        :|..:.||.....|......:....
 Worm   307 LREPLFPDVKKFELLKS-PKNIPMLTGCTNLE--------FDHESIKVPFGKYLEFENPDECDEK 362

  Fly   379 LVNDTSGLTDNILNRLLFKPQALNSHDHSAAVSSYFDLTTNIFMKSPVITLATKMYTQQRSTPVY 443
            ..||.....:|          ..|..|.:..:.....|..|..:::.|.
 Worm   363 YRNDVESGVEN----------RGNHTDKTQGIILPLKLQINNLLENNVT---------------- 401

  Fly   444 VYSFEYEGTYTRFGYEFGNSHYPFNGGVHHSNDNIYLFATHPLEGQDTQMSQKMV--DVWTSFAI 506
            .|.:||  ||.:.|              .|::|..|:...|..|..:.::..:.|  |:..:|..
 Worm   402 AYLYEY--TYPKHG--------------RHTDDLSYIMGVHAFEKDENEVHLEQVYKDMVINFIK 450

  Fly   507 EGVP 510
            .|.|
 Worm   451 LGEP 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	50..536	CDD:395084	125/494 (25%)
cest-5.1	NP_501022.3	alpha/beta hydrolases	17..495	CDD:473884	125/506 (25%)