Protein Alignment Est-Q and cest-12

DIOPT Version :9

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_499576.4
• Gene: cest-12 / 176642
• WormBaseID: WBGene00013540
• Length: 850
• Species: Caenorhabditis elegans
• Alignment Length: 574
• Identity: 144/574 - (25%)
• Similarity: 243/574 - (42%)
• Gaps: 100/574 - (17%)

  Fly    23 FLVIFLTGGQGADA--------SETATVTVELYNGQGTV------LGNYAYTAWTDRAFMQFRGI 73
            ||.:|......::|        .::..|||..  .||:|      |||.....::.:| ..|.||
 Worm     8 FLTLFSAFSNVSNAQYQNQNQNQQSNYVTVSC--SQGSVQGRQVNLGNDQSQLYSGQA-NAFTGI 69

  Fly    74 PFAEPPIEELRFRPPVARSPWTGTL-NALNFGQRCPVI-----TNLDSQMSDAELEDCLTLSVYT 132
            |:.:.|:..||.:||...:.:..|| :|..|..:||.:     ||          ||||.|:|||
 Worm    70 PYCQAPVGNLRLQPPQPLNQFNTTLHDATYFRPKCPQLNAGGPTN----------EDCLYLNVYT 124

  Fly   133 K---NLSASQPVMFYIYG-GGFYNGSSEDHPP----NYLLEKDVVLVVPQYRVGALGWLSTYTEE 189
            .   |.:|:..|:..|.| .||.||..:.:..    :.|:::.:|:|..|||:||||:.:|||..
 Worm   125 PQAGNTNANLSVLVLIDGSNGFSNGGCDQNQEKGIISNLVQRQIVVVTMQYRIGALGFFTTYTNS 189

  Fly   190 LPGNAPIADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSG 254
            :..|..:.|.:.|:.|::..|.:|||:|.::|:.||..||...|:..|||.: .|:|.:||||||
 Worm   190 VQSNLGMLDQVQAMRWIKTEIVNFGGNPNQITVAGQDDGACAVSAHCLSPMS-QNLFNQAIVQSG 253

  Fly   255 SIFASW----AINKDPKAQ---SRRICIQ----LGCSGCE-QHDQLVKCIQKAKVIDILKATASE 307
            |:::.:    |:..:|:.|   .|.:..|    .|.:|.: .:....:.|......:...|...:
 Worm   254 SVYSCYNPTPAVPTNPQVQVTTPRPMYDQSNTGYGNAGYQNNYGYQPQPITSTSSYNSANAQYDD 318

  Fly   308 SFSPIVGDLHGILP--------QQPSELVKSYRRQI--------PILTGFTQHDGSFVLASYYDA 356
            ....:...|..|.|        |.....:|:|....        |..|.....|.||:..| .|:
 Worm   319 PSQQLAQTLCNISPDQWNNGQTQNIQNCMKNYTVDFFVNQQPGGPNATWMIVRDTSFLPGS-IDS 382

  Fly   357 LAAKVANVSSLSVRQFSQGIN---DLVNDTSGLTDNILNRLLF---KPQALN---SHDHSAAVSS 412
            |..:..|:..:......:..:   .|:|...|...|.|:..:|   :...||   ::..|..:|:
 Worm   383 LTTRRPNIPIIIGTVQDEDADYAFKLINTGKGSDPNNLDDWIFDFARKNKLNQTQANQVSNIISN 447

  Fly   413 YFDLTTNIFMKSPVITLATKMYTQ-QRSTPVYVYSFEYEGTYTRFGYEFGNSHYPFNGGVHHSND 476
            .:.:.|....:.     ..::.:| |.|......:.:|:.|.   |.:..|.:....||...:|.
 Worm   448 NYGVNTGALGQQ-----GAQVNSQYQGSGTGQQVNNQYQNTQ---GQQTNNQYQYDQGGQQTNNQ 504

  Fly   477 NIYLFATHPLEGQDTQMSQKMVDVWTSFAIEGVPRNLSPLSSASGPYNKLNLEV 530
            ..|....  :.||.|....:..:.      :||.|:   ..|....|:..|.:|
 Worm   505 GAYYGGV--VAGQQTTYQNQNQNQ------QGVQRD---QGSYQNQYSNQNQQV 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	140/550 (25%)
		Aes	<137..>240	CDD:223730	38/107 (36%)
cest-12	NP_499576.4	Abhydrolase	37..>400	CDD:389770	106/377 (28%)
		Abhydrolase	<678..774	CDD:389770

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810