Protein Alignment Est-Q and ace-4

DIOPT Version :9

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_496962.1
• Gene: ace-4 / 175074
• WormBaseID: WBGene00000038
• Length: 602
• Species: Caenorhabditis elegans
• Alignment Length: 577
• Identity: 143/577 - (24%)
• Similarity: 253/577 - (43%)
• Gaps: 104/577 - (18%)

  Fly    23 FLVIFLTGGQGADASETATVTVELYNGQGTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELRFRP 87
            |:.:|:...|       |...|.|....|.:.|...:  :..:....|.|:|||||.:|:.|||.
 Worm    13 FITVFIDSVQ-------AVHPVVLETKLGDIKGTEFF--FLSKKIRTFFGVPFAEPAVEDFRFRK 68

  Fly    88 PVARSPWTGTLNALNFGQRC-------------PVITNLDSQMSDAELEDCLTLSVYTKNLSASQ 139
            |..:..|.|..:|......|             ..:.|.::|:|    ||||.|:::....:.:.
 Worm    69 PREKKQWRGLYDATKPANACFQTRDNYNTSFWGSEMWNANTQIS----EDCLYLNIWAPADAYNL 129

  Fly   140 PVMFYIYGGGFYNGSSEDHPPNYLL--------EKDVVLVVPQYRVGALGWLSTYTEELPGNAPI 196
            .||.:.:|||||:||     |:..:        .::|::|...||:|..|:|.....:.|||..:
 Worm   130 TVMVWFFGGGFYSGS-----PSLSIYDGKALTSTQNVIVVNINYRLGPFGFLYLGHPDAPGNMGL 189

  Fly   197 ADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWA 261
            .|..:||.||:.:|.||||:|.||.:|||||||....:.|::|.: ..:||.||:||||:..:||
 Worm   190 LDQQLALHWVRQNIVSFGGNPDKVAVFGQSAGAASIVAHLIAPGS-RGLFKNAILQSGSLENTWA 253

  Fly   262 INKD--PKAQSRRICIQLGCSGCEQHDQLVKCIQKAKVIDILKATASESFS----PIV---GDLH 317
            ||..  .|.:|.::...:||:.... |..:.|::......:..:|.:.|.:    |.|   .|.|
 Worm   254 INSPFRAKQKSEKLLELVGCNKTTV-DTSMACLRLVSPEQLSLSTWNISLTYLEFPFVIVSRDKH 317

  Fly   318 --GILPQQPSELVKSYRRQIPILTGFTQHDGS----FVLASYYDALAAKVANVSSLSVRQFSQGI 376
              |.|....:.....:.|.:.::.|..:.:|:    :.|..::|.     |:...|:..:|
 Worm   318 FFGHLDAHAALREGDFNRDVNLMIGMNKDEGNYWNIYQLPQFFDK-----ADPPELNRTEF---- 373

  Fly   377 NDLVNDTSGLTDNILN---RLLFKPQALNSHDHSAAVSSYF----DLTTNIFMKSPVITLATKMY 434
            :.|::.|..:..:|:.   :.::...  |..||......|.    .:..:.|.....:.||.:..
 Worm   374 DFLIDRTFSIQPDIIRSAAKYIYSDP--NCTDHGRKTRFYAGQMNQIVGDYFFSCDSLWLADQFR 436

  Fly   435 T---------QQRSTPVYVYSFEYEGTYTRFGYEFGNSHYPFNGGVHHSNDNIYLFATHPL---- 486
            :         |::...|:||.|....:         .:.:|...|..|..:..|:|.. ||
 Worm   437 SIPRVKSSSPQRKPGKVFVYHFTQSSS---------ANPWPKWTGAMHGYEIEYVFGI-PLSYSK 491

  Fly   487 --EGQDTQMSQKMVDVWTSFAIEGVPRNLSPLSSASGP-YNKLN----LEVTKGDDL 536
              :.::...|:|::..|.|||..|.|:.....:|...| :|:.|    :::..|.::
 Worm   492 NYKRREQIFSRKIMQFWASFAKNGTPKLRVLKNSEHWPEFNEQNHYRWMQLRSGSNI 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	140/561 (25%)
		Aes	<137..>240	CDD:223730	41/110 (37%)
ace-4	NP_496962.1	COesterase	28..562	CDD:278561	138/555 (25%)
		Aes	<120..>243	CDD:223730	45/128 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910