Protein Alignment Est-Q and ace-2

DIOPT Version :10

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_491141.1
• Gene: ace-2 / 171905
• WormBaseID: WBGene00000036
• Length: 629
• Species: Caenorhabditis elegans
• Alignment Length: 566
• Identity: 137/566 - (24%)
• Similarity: 234/566 - (41%)
• Gaps: 141/566 - (24%)

  Fly    70 FRGIPFAEPPIEELRFRPPVARSPWTGTLNALNFGQRCPVITNLDS---QMSDAEL--------E 123
            |.|:|:|:|||...||:.......|:|.|.|....:.|  ...:||   |...||:        |
 Worm    63 FLGVPYAKPPIGSRRFKMAEMIDRWSGELEARTLAKTC--YLTIDSAFPQFPGAEMWNPPGAISE 125

  Fly   124 DCLTLSVYTKNLSASQPVMFYIYGGGFYNGSSEDHPPN--------YLLEKDVVLVVPQYRVGAL 180
            |||.::::... .....||.:||||||::|:     |:        :..::..::|...||:|..
 Worm   126 DCLNMNIWVPE-DHDGSVMVWIYGGGFFSGT-----PSLDLYSGSVFAAKEHTIVVNVNYRLGPF 184

  Fly   181 GWLSTYTEELP--GNAPIADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASSLLLSPKTGD 243
            |:| .:.::.|  ||..:.|..:||.||..:|.:||||..:||:||:|||:...::.|.:|.: .
 Worm   185 GFL-YFGDDSPIQGNMGLMDQQLALRWVHENIGAFGGDRSRVTLFGESAGSASTTAHLFAPNS-H 247

  Fly   244 NMFKRAIVQSGSIFASWAINKDPKA--QSRRICIQLGCSGCEQHDQLVKCIQKAKVIDILKATAS 306
            ..|:..|.:||||..|||....|..  .|.|:..::.||..:. :.:|||::.... .:::|.|.
 Worm   248 KYFRNIIAKSGSIINSWASATPPTMLDLSFRLAKKVNCSSPDM-NAIVKCLRSVPA-HLVQAEAD 310

  Fly   307 E-----------SFSPIVGD---LHGILPQQPSELVKSYRRQIPILTGFTQHDGSFVLASYYDAL 357
            .           ::.|:..|   ..|.:.|:.:.  |.:::.:.|:.|..:.:|::.|..|
 Worm   311 NISGDIGPPMTFAYVPVSSDANFFQGDVFQKLAN--KQFKKDVNIIFGSVKDEGTYWLPYY---- 369

  Fly   358 AAKVANVSSLSVRQFSQGINDLVNDTSGLTDNILNRLLFKPQALNSHDH----SAAVSSYF---D 415
                     :|:.::....|..::     .::..||      ||.:.||    ..|...||   .
 Worm   370 ---------MSLPKYGFAFNHTIS-----AEDPHNR------ALITRDHYEESMRAFMPYFAGSK 414

  Fly   416 LTTNIFMKSPVITLATKMYTQQRSTP-----------------------------VYVYSFEYEG 451
            |..|.||.| ...::|....::|...                             ||:|.|.|..
 Worm   415 LVLNAFMNS-YEHVSTSNVPEERYRDGVARFLGDLFFTCSLIDFADLISDNIFGNVYMYYFTYRS 478

  Fly   452 TYTRFGYEFGNSHYPFNGGVHHSNDNIYLFA-----------THPLEGQDTQMSQKMVDVWTSFA 505
            :         .:.:|...||.|..:..|.|.           || || .:.::|..::.:|.:||
 Worm   479 S---------ANPWPKWMGVMHGYEIEYAFGQPYWRPHLYDQTH-LE-DEKRLSSIIMQIWANFA 532

  Fly   506 IEGVPRNLSPLSSASGPYNKLNLE-VTKGDDLLDTLTAAIDDPDNG 550
            ..|...:..|      .|||:..: :..|:..|......|.|...|
 Worm   533 NTGRTDSFWP------QYNKIERKAIELGETTLQGKHRIISDVHGG 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	50..536	CDD:395084	133/550 (24%)
ace-2	NP_491141.1	COesterase	40..558	CDD:395084	133/550 (24%)