Protein Alignment Est-Q and Cel

DIOPT Version :9

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_034015.1
• Gene: Cel / 12613
• MGIID: 88374
• Length: 599
• Species: Mus musculus
• Alignment Length: 638
• Identity: 186/638 - (29%)
• Similarity: 260/638 - (40%)
• Gaps: 176/638 - (27%)

  Fly    15 VLTAGLTAFLVIFLTGGQGADASETATVTVELYNGQGTVLGNYAYTAWTDRAFMQFRGIPFAEPP 79
            ||..|||..|........||..:|..  .||..|.:.::||..:...        |:|||||...
Mouse     6 VLFLGLTCCLAAACAAKLGAVYTEGG--FVEGVNKKLSLLGGDSVDI--------FKGIPFATAK 60

  Fly    80 IEELRFRPPVARSPWTGTLNALNFGQRCPVITNLDSQMSDAELEDCLTLSVYT----KNLSASQP 140
            ..|...|.|    .|.|||.|.||.:||...|  .:|.:....||||.|:::.    |.:|.:.|
Mouse    61 TLENPQRHP----GWQGTLKATNFKKRCLQAT--ITQDNTYGQEDCLYLNIWVPQGRKQVSHNLP 119

  Fly   141 VMFYIYGGGFYNGSSE--DHPPNYLLEKD-------VVLVVPQYRVGALGWLSTYTEELPGNAPI 196
            ||.:||||.|..||.:  :...|||.:.:       |::|...||||.||:|||....||||..:
Mouse   120 VMVWIYGGAFLMGSGQGANFLKNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNFGL 184

  Fly   197 ADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWA 261
            .|..||:.||:.:|::|||||..:||||:||||...|...||| ....:.:|||.|||...:.||
Mouse   185 RDQHMAIAWVKRNIAAFGGDPDNITIFGESAGAASVSLQTLSP-YNKGLIRRAISQSGMALSPWA 248

  Fly   262 INKDPKAQSRRICIQLGCSGCEQHDQLVKCIQKAKVIDILKATASESFSPIVGDLHGILPQQPSE 326
            |.|:|...::.|..::||. .|...::..|:   |:.|....|.:..           ||.:..|
Mouse   249 IQKNPLFWAKTIAKKVGCP-TEDTGKMAACL---KITDPRALTLAYK-----------LPVKKQE 298

  Fly   327 L-VKSYRRQIPILTGFTQHDGSFVLASYYDALAAKVANVSSLSVRQFSQGINDLVNDTSGLTDNI 390
            . |..|...||::      ||.|:.....: |....|::..::      |||::        |..
Mouse   299 YPVVHYLAFIPVI------DGDFIPDDPIN-LYNNTADIDYIA------GINNM--------DGH 342

  Fly   391 LNRLLFKP------QALNSHDHSAAVSSY------------FDLTTNIF--------MKSPVITL 429
            |...:..|      |.:...|....||.:            ||:.|..:        ||..|:..
Mouse   343 LFATIDVPAVDKTKQTVTEEDFYRLVSGHTVAKGLKGAQATFDIYTESWAQDPSQENMKKTVVAF 407

  Fly   430 ATKMY-------------TQQRSTPVYVYSFEYEGTYTRFGYEFGNSH------YPFNGGVHHSN 475
            .|.:.             ...:|...|.|.|               ||      ||...|..|::
Mouse   408 ETDVLFLIPTEIALAQHKAHAKSAKTYSYLF---------------SHPSRMPIYPKWMGADHAD 457

  Fly   476 DNIYL----FATHPL--EGQDTQMSQKMVDVWTSFAIEGVPRNL--SPLSSASGPYNKLN---LE 529
            |..|:    ||| ||  ..||..:|:.|:..||:||..|.| |:  ||:.:...||...|   |:
Mouse   458 DLQYVFGKPFAT-PLGYRPQDRAVSKAMIAYWTNFARSGDP-NMGNSPVPTHWYPYTLENGNYLD 520

  Fly   530 VTK------------------------------GDDLLDTLTAAIDD----PD 548
            :||                              ||.  ||||...||    ||
Mouse   521 ITKTITSASMKEHLREKFLKFWAVTFEVLPTVTGDQ--DTLTPPEDDSEVAPD 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	173/604 (29%)
		Aes	<137..>240	CDD:223730	50/111 (45%)
Cel	NP_034015.1	COesterase	26..542	CDD:278561	168/585 (29%)
		Aes	<117..>247	CDD:223730	57/130 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	553..599		10/21 (48%)
		4 X 11 AA tandem repeats, O-glycosylated region	559..588		6/13 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810