DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Est-Q and LOC107987423

DIOPT Version :9

Sequence 1:	NP_649321.1	Gene:	Est-Q / 40381	FlyBaseID:	FBgn0037090	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	XP_016885725.1	Gene:	LOC107987423 / 107987423	-ID:	-	Length:	286	Species:	Homo sapiens

Alignment Length:	254	Identity:	43/254 - (16%)
Similarity:	98/254 - (38%)	Gaps:	57/254 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 LVKCIQKAKVIDILKATASESF------------SPIVGD-LHGILPQQPSELVKSYR--RQIPI 337
            :|.|:::....::|:.|....|            .|::|. :.|:|..:..|.:::.|  ..:|.
Human     1 MVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPY 65

  Fly   338 LTGFTQHDGSFVLASY---YDALAAKVANVSSLSVRQFSQGI----NDLVNDTS-----GLTDNI 390
            :.|..:.:..:::...   |.....::...:::|:...|..:    .:|:.:.:     |..|.:
Human    66 MVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTV 130

  Fly   391 LNRLLFKPQALNSHDHSAAVSSYFDLTTNIFMKSPVITLATKMYTQQRSTPVYVYSFEYEGTYTR 455
            ..:.||                 .||..::....|.:.:|..  .:....|.|:|.|:|..:
Human   131 KKKDLF-----------------LDLIADVMFGVPSVIVARN--HRDAGAPTYMYEFQYRPS--- 173

  Fly   456 FGYEFGNSHYPFNGGVHHSNDNIYLFATHPL-EG---QDTQMSQKMVDVWTSFAIEGVP 510
                |.:...|......|.::...:|....| ||   ::.::|:.::..|.:||..|.|
Human   174 ----FSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNP 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	43/254 (17%)
Est-Q	NP_649321.1	Aes	<137..>240	CDD:223730
LOC107987423	XP_016885725.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010