Protein Alignment Est-Q and Ces2a

DIOPT Version :9

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_598721.1
• Gene: Ces2a / 102022
• MGIID: 2142491
• Length: 558
• Species: Mus musculus
• Alignment Length: 544
• Identity: 142/544 - (26%)
• Similarity: 236/544 - (43%)
• Gaps: 95/544 - (17%)

  Fly    12 LCGVLTAGLTAFLVIFLTGGQGADASETATVTVELYNGQGTVLGNYAYTAWTDRAFMQFRGIPFA 76
            || |:..||...|       |.....::|:.....:.||  |.|::.:...|......|.|||||
Mouse    10 LC-VVACGLLLLL-------QHVHGQDSASPIRNTHRGQ--VRGSFVHVKDTKSGVHAFLGIPFA 64

  Fly    77 EPPIEELRFRPPVARSPWTGTLNALNFGQRC--PVITNLDSQMSDAE-----------LEDCLTL 128
            :||:..|||.||....||:|..:..:....|  |.|.||:    ||:           .||||.|
Mouse    65 KPPVGLLRFAPPEDPEPWSGVRDGTSQPAMCLQPDIMNLE----DAKEMNLILPPISMSEDCLYL 125

  Fly   129 SVYTKNLS---ASQPVMFYIYGGGFYNGSSEDHPPNYL-LEKDVVLVVPQYRVGALGWLSTYTEE 189
            ::||...:   ::.|||.:|:|||...||:..:..:.| ..:::|:|..|||:|.||:.||..:.
Mouse   126 NIYTPTHAQEGSNLPVMVWIHGGGLVVGSASMNDVSKLAATEEIVIVAIQYRLGVLGFFSTGDQH 190

  Fly   190 LPGNAPIADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSG 254
            ..||....|.:.||.|||.:|:.|||:..:|||||.|||....||.:|||.: ..:|..||:|||
Mouse   191 ARGNWGYLDQVAALRWVQKNIAYFGGNRDRVTIFGVSAGGTSVSSHILSPMS-KGLFHGAIMQSG 254

  Fly   255 SIFASWAINKDPKAQSRRICIQLGCSGCEQHDQ--LVKCIQKAKVIDILKATASESFSPIVGDLH 317
            .......|:...:...:.:.   ..||||..|.  |:.|::.....:||.........|.|.| .
Mouse   255 VALLPDLISDTSEVVYKTVA---NLSGCEATDSEALIHCLRAKSKQEILAINQVFKMIPAVVD-G 315

  Fly   318 GILPQQPSELVKSYR-RQIPILTGFTQHDGSFVLASYYDALAAKVANVSSLSVRQFSQGINDLVN 381
            ..||:.|.||:.|.. ..:|.:.|....:..:.:..:                    .|::.::.
Mouse   316 EFLPKHPQELLTSMDFHPVPSIIGVNTDECGWGVPMF--------------------MGLDHIIK 360

  Fly   382 DTS-----GLTDNILNRLLFKPQALNSH-----------DHSAAVSSYFDLTTNIFMKSPVITLA 430
            :.:     .:..|...|::..|:.  ||           |.....:.:.::..:.....|.:.:|
Mouse   361 NITRETLPAVLKNTAARMMLPPEC--SHLLVEEYMGDTEDPETLQAQFREMLGDFMFVIPALQVA 423

  Fly   431 TKMYTQQRSTPVYVYSFEYEGTYTRFGYEFGNSHY-PFNGGVHHSNDNIYLFATH------PLEG 488
               :.|:...|||.|.|::..::.:        |. |.:....|.:|..::|.::      .|..
Mouse   424 ---HFQRSQAPVYFYEFQHLSSFIK--------HVRPSHVKADHGDDVAFVFGSYLWDMNLDLTE 477

  Fly   489 QDTQMSQKMVDVWTSFAIEGVPRN 512
            ::..:.:.|:..|.:||..|.|.:
Mouse   478 EEELLKRMMMKYWANFARNGNPNS 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	135/517 (26%)
		Aes	<137..>240	CDD:223730	44/103 (43%)
Ces2a	NP_598721.1	COesterase	30..537	CDD:278561	135/516 (26%)
		Aes	<127..>230	CDD:223730	41/102 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810