DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Est-Q and LOC100493994

DIOPT Version :9

Sequence 1:	NP_649321.1	Gene:	Est-Q / 40381	FlyBaseID:	FBgn0037090	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	XP_004913616.1	Gene:	LOC100493994 / 100493994	-ID:	-	Length:	568	Species:	Xenopus tropicalis

Alignment Length:	540	Identity:	148/540 - (27%)
Similarity:	233/540 - (43%)	Gaps:	87/540 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 TVELYNGQ----------GTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELRFRPPVARSPWTGT 97
            |:|:|..:          |.:|||......|||....|.|:|||:|||..|||..|....||:..
Frog    25 TLEIYGTEDARPLLTTKYGQLLGNTVGAKETDRLVHVFMGVPFAKPPIGPLRFEAPQPPEPWSSV 89

  Fly    98 LNALNFGQRCPVITNLDSQ-MSD-AEL-----------EDCLTLSVYT---KNLSASQPVMFYIY 146
            ..|    ...|.:...|.: |.| ||.           ||||.|:|:|   :..:...|||.:|:
Frog    90 REA----TAAPPMCLQDKRGMEDLAEFFKAKFDFPPVSEDCLYLNVFTPADRGENPELPVMVFIH 150

  Fly   147 GGGFYNGSSEDHPPNYLLE-KDVVLVVPQYRVGALGWLSTYTEELPGNAPIADILMALDWVQMHI 210
            ||....|.:.....:.|.. ::||:|..|||:|.:|:.|:..:|:.||....|.:.||.||:.:|
Frog   151 GGALTMGGASMFEGSALCAYENVVVVSIQYRLGIMGFFSSGDKEVRGNFGFLDQVAALQWVRDNI 215

  Fly   211 SSFGGDPQKVTIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWAINKDPKAQSRRICI 275
            ..|||:||.|||||:|||....|:.:||| ....:|.:||.:||.......:....:.....:.:
Frog   216 KDFGGNPQSVTIFGESAGGVSVSAQVLSP-LSKGLFHKAIAESGVAILPGLMTSKTEEILPLLSV 279

  Fly   276 QLGCSGCEQHDQLVKCIQKAKVIDILKATASESFSPIVGDLHGILPQQPSE--LVKSYRRQIPIL 338
            ....|.|...| ||.|::|....:|:..||:..|......:.|:...:|:|  |.......:|.|
Frog   280 VANISSCSVSD-LVGCLKKKTEDEIIAITAAMRFLVFPAVVDGVFLPKPAEEILAAKESNPVPFL 343

  Fly   339 TGFTQHDGSFVL------ASYYDALAAK--VANVSSLS-VRQFSQGINDLVNDTSGLTDNILNRL 394
            .|...|:..::|      ..|.:.:..|  .|.:.:|. :...|..|..::.:..|.||:
Frog   344 IGINNHEFGWILPLSLNITGYREGMEKKNIQATLGALPLLNTVSSAIPFIMEEYFGDTDD----- 403

  Fly   395 LFKPQALNSHDHSAAVSSYFDLTTNIFMKSPVITLATKMYTQQRSTPVYVYSFEYEGTYTRFGYE 459
               |:.|.        :::.||..:|....|  .|.|..|.:....|||.|.|::..:.
Frog   404 ---PKELR--------NNFLDLVGDIIFVIP--ALRTAKYHRDSGFPVYFYEFQHRPSM------ 449

  Fly   460 FGNSHYPFNGGVHHSNDNIY------------LFATHPLEGQDTQMSQKMVDVWTSFAIEGVPRN 512
            :.:|...|....|  .|.:|            ||.::..| ::..:|:.::..|.:||..|.|..
Frog   450 YADSKDDFVKADH--GDELYFVVGGPFLKSGILFKSNGTE-EEKILSKTIMKYWANFARNGDPNG 511

  Fly   513 LS----PLSSASGPYNKLNL 528
            |.    |.......|.::||
Frog   512 LGLAEWPKYDEDEDYLEINL 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	148/540 (27%)
Est-Q	NP_649321.1	Aes	<137..>240	CDD:223730	42/103 (41%)
LOC100493994	XP_004913616.1	COesterase	36..547	CDD:365897	145/529 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000