DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Est-Q and bchel

DIOPT Version :9

Sequence 1:	NP_649321.1	Gene:	Est-Q / 40381	FlyBaseID:	FBgn0037090	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	XP_002937472.3	Gene:	bchel / 100135377	XenbaseID:	XB-GENE-5842192	Length:	559	Species:	Xenopus tropicalis

Alignment Length:	563	Identity:	157/563 - (27%)
Similarity:	254/563 - (45%)	Gaps:	117/563 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RRGVYVMLTLCGVLTAGLTAFLVIFLTGGQGADASETATVTVELYNGQGTVLG-NYAYTAWTDRA 66
            :|..:..|.:|.:    |.:||::      ..:|.....|.|:    ||.|.| |.:..:....|
Frog     5 KRNCFRCLQVCNL----LMSFLIL------STNAGHENIVEVK----QGKVSGINLSVKSGYVTA 55

  Fly    67 FMQFRGIPFAEPPIEELRFRPPVARSPWTGTLNALNFGQRCPVITNLDSQMSD---AEL------ 122
            ::   |||:.|||...|||:....|.||.|.|.|..||:.|  ..|.:::.::   .|:
Frog    56 YL---GIPYGEPPTGRLRFKKTEQRKPWHGVLKADKFGKSC--FQNRENKFAEFPGTEMFLVNNE 115

  Fly   123 --EDCLTLSVYTKNLSASQP----VMFYIYGGGF---------YNGSSEDHPPNYLLEKDVVLVV 172
              ||||.|:|:   :..|:|    ||.:|:||||         |:||...:..|      |::|.
Frog   116 MSEDCLHLNVW---VPPSKPKDAHVMVFIHGGGFESGTTSLDIYDGSVLAYAEN------VIVVS 171

  Fly   173 PQYRVGALGWLS-TYTEELPGNAPIADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASSLL 236
            ..|||||.|:|: ...::.||||.:.|..:||.|:..:|::|||:|.:|||||.||||......|
Frog   172 MNYRVGAFGFLALPGHKDAPGNAGLFDQRLALQWINENIAAFGGNPDRVTIFGHSAGAASVGFHL 236

  Fly   237 LSPKTGDNMFKRAIVQSGSIFASWAINKDPKAQSRRICIQLG-CSGCEQ--HDQLVKCI--QKAK 296
            :|||:.. .:.||||||||..::||:|.:.:|  :|:.::|. ...|.|  .|.::.|:  :..|
Frog   237 ISPKSYP-YYNRAIVQSGSGTSNWALNSEERA--KRLALKLAEVLECPQTDDDAIITCLLNEDPK 298

  Fly   297 VIDILKATASE-----SFSPIVGDLHGILPQQPSELVKSYRRQIPILTGFTQHDGS-FVLASYYD 355
            .:...:..|.|     .|.|||.  |..|...|..::....::..||.|.|:.||: |.|....|
Frog   299 HLTEKQLLAKEPYALTQFLPIVD--HDFLVDVPENVLGQSMKRTDILLGITKDDGNPFTLIGSTD 361

  Fly   356 ALAAKVANVSSLS----VRQFSQGINDL--------VNDTSGLTDNILNRLLFKPQALNSHDHSA 408
            ......:::||..    :::|.....||        ..|...:.:...||     ||:..
Frog   362 FNIQTESSISSAELLERLKRFFPSAGDLGIQSILLQYKDWEDVNNGEKNR-----QAMEL----- 416

  Fly   409 AVSSYFDLTTNIFMKSPVITLATKMYTQQRSTPVYVYSFEYEGTYTRFGYEFGNSHYPFNGGVHH 473
                   :..:.:...||...|  .|..:....|:.|.:::..:         |..:|...|..|
Frog   417 -------ILRDYYFACPVKGFA--RYAVEHQNNVFFYEYDHRSS---------NDPWPEWMGALH 463

  Fly   474 SNDNIYLFATHPL--EGQDTQ----MSQKMVDVWTSFAIEGVP 510
            ..:...||. .|.  :|:.|:    .|::::.:|.:||..|.|
Frog   464 GAELPMLFG-KPFINKGRYTRSELLFSKRIMKLWANFARTGSP 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	150/527 (28%)
Est-Q	NP_649321.1	Aes	<137..>240	CDD:223730	46/116 (40%)
bchel	XP_002937472.3	COesterase	31..547	CDD:395084	150/527 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910