Protein Alignment Est-Q and nlgn2b

DIOPT Version :10

• Sequence 1: NP_649321.1
• Gene: Est-Q / 40381
• FlyBaseID: FBgn0037090
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 575
• Identity: 157/575 - (27%)
• Similarity: 249/575 - (43%)
• Gaps: 117/575 - (20%)

  Fly     5 GVYVMLTLCGVLTAGLTAFLVIFLTGGQGADASETATVTVELYNGQGTVLGNYAYTAWTDRAFMQ 69
            |:.:.|.|.....|.||......:|.|.|    :...|..||.|   .:||          ...|
Zfish    31 GLALRLALSSCQRADLTTAKHPMVTTGYG----KLRGVRKELNN---EILG----------PVEQ 78

  Fly    70 FRGIPFAEPPIEELRFRPPVARSPWTGTLNALNFGQRCP---------------VITNLDSQMS- 118
            :.|:|:|.||:.|.||:||.|...|....||..|...||               ...|||:..:
Zfish    79 YLGVPYATPPVGERRFQPPEAPGSWQEIRNATQFAPVCPQNIHGVLPEIMLPVWFTDNLDAAAAY 143

  Fly   119 -DAELEDCLTLSVY--------TKNLSAS---------------QPVMFYIYGGGFYNGSSEDHP 159
             ..:.||||.|:||        ||....|               :|||.:|:||.|..|:.....
Zfish   144 VQNQSEDCLYLNVYVPTEDGPLTKKHDESSMNRPRDEDIRDRRKKPVMLFIHGGSFMEGTGNMFD 208

  Fly   160 PNYLLE-KDVVLVVPQYRVGALGWLSTYTEELPGNAPIADILMALDWVQMHISSFGGDPQKVTIF 223
            .:.|.. .:|::|...||:|.||:||:..:...||..:.|.:.||.|:..:|..|||||:::|||
Zfish   209 ASVLAAYGNVIVVTMNYRLGVLGFLSSGDQSAKGNYGLLDQIQALRWLNENIGHFGGDPERITIF 273

  Fly   224 GQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWAINKDPKAQSRRICIQLGCSGCEQHDQL 288
            |..|||...:.|:||..: :.:|:|||.||||..:||::|..|...::.:..::|||..:..| |
Zfish   274 GSGAGASCVNLLILSHHS-EGLFQRAIAQSGSAISSWSVNYRPLMYTKILAKKVGCSYSDTAD-L 336

  Fly   289 VKCIQKAKV-----IDILKATASESFSPIV-GDLHGILPQQPSELVK-----SYRRQIPILTGFT 342
            |.|:::...     .|:..|....:|.|:| ||   ::|..|..|::     :|    .||.|..
Zfish   337 VDCLRRKSYRELVDQDVQPARYHIAFGPVVDGD---VVPDDPEILMQQGEFLNY----DILLGVN 394

  Fly   343 QHDGSFVLASYYDALAAKVANVSSLSVRQFSQGINDLVNDTSGLTD--NILN---RLLFKPQALN 402
            |.:|    ..:.|....:    ..:|...|...|::.|::..|..:  :||.   :.::...| :
Zfish   395 QGEG----LKFVDDNEGE----EGISAASFDYTISNFVDNLYGYPEGKDILRETIKFMYTDWA-D 450

  Fly   403 SHDHSAAVSSYFDLTTNIFMKSPVITLATKMYTQQRSTPVYVYSFEYE-GTYTRFGYEFGNSHYP 466
            ..:......:...|.|:....:|.:..| |::.:.:| |||.|:|.:. .|..|          |
Zfish   451 RDNGDMRRKTLLALFTDHQWVAPAVATA-KLHAEFQS-PVYFYTFHHHCQTEAR----------P 503

  Fly   467 FNGGVHHSNDNIYLFATHPLEG-----------QDTQMSQKMVDVWTSFAIEGVP 510
            ......|.::..|:|.. |:.|           .|..:|..::..||:||..|.|
Zfish   504 EWADAAHGDEIPYVFGV-PMVGATELFPCNFSKNDIMLSAVVMTYWTNFAKTGDP 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-Q	NP_649321.1	COesterase	50..536	CDD:395084	144/530 (27%)
nlgn2b	NP_001159808.1	COesterase	52..611	CDD:395084	151/554 (27%)