Protein Alignment Hr78 and rxraa

DIOPT Version :10

• Sequence 1: NP_730636.1
• Gene: Hr78 / 40378
• FlyBaseID: FBgn0015239
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_005161240.1
• Gene: rxraa / 555578
• ZFINID: ZDB-GENE-070314-2
• Length: 500
• Species: Danio rerio
• Alignment Length: 600
• Identity: 125/600 - (20%)
• Similarity: 198/600 - (33%)
• Gaps: 264/600 - (44%)

  Fly    10 IKSEENRAMPLIGGG-----SASGGTPLPGGGVGMGAGASATLSVELCLVCGDRASGRHYGAISC 69
            :.|.|:...||...|     :...||||             :|:..:|.:||||:||:|||..||
Zfish   134 VSSSEDIKPPLGLNGVMKVPAQPSGTPL-------------SLTKHICAICGDRSSGKHYGVYSC 185

  Fly    70 EGCKGFFKRSIRKQLGYQCRGAMNCEVTKHHRNRCQFCRLQKCLASGMRSDSVQHERKPIVDRKE 134
            |||||||||::||.|.|.||...:|.:.|..|||||:||.|||||.||:.:.:.|.
Zfish   186 EGCKGFFKRTVRKDLTYTCRDNKDCVIDKRQRNRCQYCRYQKCLAMGMKREVLLHT--------- 241

  Fly   135 GIIAAAGSSSTSGGGNGSSTYLSGKSGYQQGRGKGHSVKAESAATPPVHSAPATAFNLNENIFPM 199
                                                                             
Zfish   242 ----------------------------------------------------------------- 241

  Fly   200 GLNFAELTQTLMFATQQQQQQQQQHQQSGSYSPDIPKADPEDDEDDSMDNSSTLCLQLLANSASN 264
                         |.|:::|:.::..::                            ::.:.|::|
Zfish   242 -------------AVQEERQRAKERSEN----------------------------EVESTSSAN 265

  Fly   265 NNSQHLNFNAGEVPTALPTTSTMGLIQSSLDMRVIHKGLQILQPIQNQLERNGNLSVKPECDSEA 329
            .                             ||           |::..||  ..|:|:|:.::
Zfish   266 E-----------------------------DM-----------PVEKILE--AELAVEPKTET-- 286

  Fly   330 EDSGTEDAVDAELEHMELDFECGGNRSGGSDFAINEAVFEQDLLTDVQCAFHVQPPTLVHSYLNI 394
                          ::|.:.....|.             ..|.:|:
Zfish   287 --------------YIETNVPMPSNS-------------PNDPVTN------------------- 305

  Fly   395 HYVCETGSRIIFLTIHTLRKVPVFEQLEAHTQVKLLRGVWPALMAIALAQCQGQLSVPTIIGQFI 459
              :|:...:.:|..:...:::|.|.:|....||.|||..|..|                :|..|
Zfish   306 --ICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNEL----------------LIASF- 351

  Fly   460 QSTRQLADIDKI---EPLKISKM--------ANLTRTLHDFVQELQSLDVTDMEFGLLRLILLFN 513
             |.|.:|..|.|   ..|.:.:.        |...|.|.:.|.:::.:.:...|.|.||.|:|||
Zfish   352 -SHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFN 415

  Fly   514 PT---LLQQRKERSLRGYV-RRVQLYALSSLRRQGGIGGGEERFNVLVARLLPLSSLDAEAMEEL 574
            |.   |....:..:||..| ..::.|.......|.|      ||..|:.||..|.|:..:.:|.|
Zfish   416 PDSKGLSNPGEVEALREKVYASLEAYCKHKYPEQPG------RFAKLLLRLPALRSIGLKCLEHL 474

  Fly   575 FFANLVGQMQMDALI 589
            ||..|:|...:|..:
Zfish   475 FFFKLIGDTPIDTFL 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr78	NP_730636.1	NR_DBD_TR2_like	47..133	CDD:143525	45/85 (53%)
		NR_LBD_TR2_like	372..595	CDD:132750	55/232 (24%)
rxraa	XP_005161240.1	Nuc_recep-AF1	63..160	CDD:463363	6/25 (24%)
		NR_DBD_RXR	166..247	CDD:143514	46/167 (28%)
		NR_LBD_RXR_like	267..478	CDD:132741	63/297 (21%)