Protein Alignment Hr78 and nr2c1

DIOPT Version :9

• Sequence 1: NP_001189151.1
• Gene: Hr78 / 40378
• FlyBaseID: FBgn0015239
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001018458.1
• Gene: nr2c1 / 553649
• ZFINID: ZDB-GENE-041210-198
• Length: 600
• Species: Danio rerio
• Alignment Length: 632
• Identity: 179/632 - (28%)
• Similarity: 280/632 - (44%)
• Gaps: 143/632 - (22%)

  Fly     9 FIKSEENRAMPLIGGGSASGGTPLPGGGVGMGAGASATLS-------------------VELCLV 54
            |||.|.:.|..::        |...|..|.....||..||                   ||.|:|
Zfish    59 FIKQENSPAKVIL--------TSSDGSAVNQLLFASPELSGQQIQFVTDGSDQGSMKPPVEYCVV 115

  Fly    55 CGDRASGRHYGAISCEGCKGFFKRSIRKQLGYQCRGAMNCEVTKHHRNRCQFCRLQKCLASGMRS 119
            |||:||||||||:|||||||||||||||.|.|.|||:..|.:.||||||||:||||:|:|.||:.
Zfish   116 CGDKASGRHYGAVSCEGCKGFFKRSIRKNLVYTCRGSGECVINKHHRNRCQYCRLQRCMALGMKQ 180

  Fly   120 DSVQHERKPIVDRKEGIIAAAGSSSTSGGGNGSSTYLSGKSGYQQGRGKGHSVKAESAATPPVHS 184
            ||||.||||:                                             |.:...|.:.
Zfish   181 DSVQCERKPV---------------------------------------------EVSREKPANC 200

  Fly   185 APATAFNLNENIFPMGLNFAELTQTLMFATQQQQQQQQQHQQSG---SYSPDIPKADPEDDEDDS 246
            ||:.     |.|:......:.|.....|.:|::..:......|.   :....|.|.|
Zfish   201 APSI-----EKIYIRKNLCSPLAAMPTFVSQKESTRPTSLLDSNMLLNIQQSISKLD-------- 252

  Fly   247 MDNSSTLCLQLLANSASNNNSQHLNFNAGEVPTALPTTSTMGLIQSSLDMRVIHKGLQILQPIQN 311
                :|:   |:.:|...|:|     :.|::.|.....:::|.:..|.:|......|..:..:.|
Zfish   253 ----NTI---LIPSSPDQNDS-----SQGDLGTLANVVTSLGRLNKSREMMDSSTDLSGIDTMSN 305

  Fly   312 QLERNGNLSVKPECDSEAEDSGTEDAVDAELEHMELDFECGGNRSGGS----DFAINEAVFEQD- 371
                  :.||..:...| |.:....|.|...:.::.:..||...:.|:    |.....|:.|.:
Zfish   306 ------DDSVMTDIQRE-ESNDVTRAFDTLTKVLKAEESCGEEVADGAVAVRDDEQTSALLELEG 363

  Fly   372 -LLTDVQCAFHVQPPTLVHSYLNIHYVCETGSRIIFLTIHTLRKVPVFEQLEAHTQVKLLRGVWP 435
             ||:|:...|.:..|..:..:||::|:||:.||::||::|..|.:|.|:.|.:...:.|::..|.
Zfish   364 PLLSDMHVPFKLMMPLPMPDFLNLNYICESASRLLFLSMHWARSIPAFQALGSENGITLMKACWN 428

  Fly   436 ALMAIALAQCQGQLSVPTIIGQFIQSTRQLADIDKIEPLKISKMANLTRTLHDFVQELQSLDVTD 500
            .|.|:.||||...::|.||:...|...:...|.:|:.|.::.::......:.:|...:..:....
Zfish   429 ELFALGLAQCSHIMNVETILTAIINHLQTSLDEEKLSPERVKQVMEHIWRMQEFCNSMSRMSPDA 493

  Fly   501 MEFGLLRLILLFNP-------TL----LQQRKERSLRGYVRRV---QLYALSSLRRQGGIGGGEE 551
            .|:..|:.::||:|       ||    .|::....|:.||.:|   ..|.||.
Zfish   494 YEYAYLKAVVLFSPDHSAVDGTLQIERFQEKAYMELQDYVSKVYPEDTYRLSK------------ 546

  Fly   552 RFNVLVARLLPLSSLDAEAMEELFFANLVGQMQMDALIPFILMTSNT 598
                |:.||..|..:.|...||||||.|:|.:|:|::||:||...:|
Zfish   547 ----LLVRLPALRLMSAAVTEELFFAGLIGNVQIDSIIPYILKMEST 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr78	NP_001189151.1	NR_DBD_TR2_like	47..133	CDD:143525	62/104 (60%)
		NR_LBD_TR2_like	372..595	CDD:132750	69/236 (29%)
nr2c1	NP_001018458.1	NR_DBD_TR2_like	108..194	CDD:143525	61/130 (47%)
		NR_LBD_TR2_like	365..586	CDD:132750	69/236 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577486
Domainoid	1	1.000	123	1.000	Domainoid score	I5538
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3011
OMA	1	1.010	-	-		QHG45830
OrthoDB	1	1.010	-	-		D145512at33208
OrthoFinder	1	1.000	-	-		FOG0002998
OrthoInspector	1	1.000	-	-		otm24645
orthoMCL	1	0.900	-	-		OOG6_106195
Panther	1	1.100	-	-	LDO	PTHR24083
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1991
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.870