Protein Alignment Hr78 and nr2c1

DIOPT Version :10

• Sequence 1: NP_730636.1
• Gene: Hr78 / 40378
• FlyBaseID: FBgn0015239
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001016207.1
• Gene: nr2c1 / 548961
• XenbaseID: XB-GENE-484727
• Length: 636
• Species: Xenopus tropicalis
• Alignment Length: 565
• Identity: 179/565 - (31%)
• Similarity: 265/565 - (46%)
• Gaps: 113/565 - (20%)

  Fly    49 VELCLVCGDRASGRHYGAISCEGCKGFFKRSIRKQLGYQCRGAMNCEVTKHHRNRCQFCRLQKCL 113
            ||||:||||:||||||||::||||||||||||||.|.|.|||:.:|.:.||:|||||:||||:|:
 Frog   149 VELCVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYTCRGSKDCVINKHYRNRCQYCRLQRCI 213

  Fly   114 ASGMRSDSVQHERKPI-VDRKEGIIAAAGSSSTSGGGNGSSTYLSGKSGYQQGRGKGHSVKAESA 177
            |.||:.||||.||||| |.|::....||.:         ...|:.            ..:::..|
 Frog   214 ALGMKQDSVQCERKPIEVSREKSSNCAAST---------EKIYIR------------KDLRSPLA 257

  Fly   178 ATPPVHSAPATAFNLNENIFPMGLNFAELTQTLMFATQQQQQQQQQHQQSGSYSPDIPKADPEDD 242
            ||        |.| :.||      ..:..|..|........||.....:|...:|        :.
 Frog   258 AT--------TTF-VTEN------KTSRTTSLLDSGMLVNIQQSGVKNESILITP--------NK 299

  Fly   243 EDDSMDNSSTLCLQLLANSASNNNSQHLNFNAGEVPTALPTTSTMGLIQSSLDMRVIHKGLQILQ 307
            .|....:.|||. .::.:.|:.|.|:.           ||.|:|               .|.|::
 Frog   300 VDACQGDLSTLA-NVVTSLANLNKSKE-----------LPQTNT---------------ELSIIE 337

  Fly   308 PIQNQLERNGNLSVKPECD-SEAEDSGTEDAVDAELEHMEL----DFECGGNRSGGSDFAINEAV 367
            .:.|   .:.:||...:.| |.:|.:...|.:...|...|.    ..||.|:.|..:|..:.
 Frog   338 SLSN---GDSSLSELAQDDQSNSEVTRAFDTLAKALNQSENSAQGSSECVGSNSNLTDANVE--- 396

  Fly   368 FEQDLLTDVQCAFHVQPPTLVHSYLNIHYVCETGSRIIFLTIHTLRKVPVFEQLEAHTQVKLLRG 432
            .|..||:|...||.:..|:.:..|||:||:||:.||::||::|..|.:|.|:.|.....:.|::.
 Frog   397 IEGPLLSDAHIAFRLTMPSPMPEYLNVHYICESASRLLFLSMHWARSIPSFQSLGQENSISLVKA 461

  Fly   433 VWPALMAIALAQCQGQLSVPTIIGQFIQSTRQLADIDKIEPLKISKMANLTRTLHDFVQELQSLD 497
            .|..|.::.||||...::|.||:..|:.........||:...|:..:.:....|.:|...:..|.
 Frog   462 CWNELFSLGLAQCCQVMNVETILAAFVNHLHNSMQHDKLSADKVKLVMDHIFKLQEFCNSMVKLS 526

  Fly   498 VTDMEFGLLRLILLFNP-----------TLLQQRKERSLRGYVRRV---QLYALSSLRRQGGIGG 548
            |...|:..|:.|.||:|           ..||::.....:.||.:.   ..|.||.
 Frog   527 VDGYEYAYLKAIALFSPDHPGLENVSHIEKLQEKAYMEFQDYVTKTYPEDTYRLSR--------- 582

  Fly   549 GEERFNVLVARLLPLSSLDAEAMEELFFANLVGQMQMDALIPFIL 593
                   |:.||..|..|:|...||||||.|:|.:|:|::||:||
 Frog   583 -------LLLRLPALRLLNAAITEELFFAGLIGNVQIDSIIPYIL 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr78	NP_730636.1	NR_DBD_TR2_like	47..133	CDD:143525	61/84 (73%)
		NR_LBD_TR2_like	372..595	CDD:132750	73/236 (31%)
nr2c1	NP_001016207.1	NR_DBD_TR2_like	147..233	CDD:143525	61/83 (73%)
		NR_LBD_TR2_like	401..622	CDD:132750	73/236 (31%)