Protein Alignment Hr78 and hnf4a

DIOPT Version :9

• Sequence 1: NP_001189151.1
• Gene: Hr78 / 40378
• FlyBaseID: FBgn0015239
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_021325423.1
• Gene: hnf4a / 322358
• ZFINID: ZDB-GENE-030131-1077
• Length: 470
• Species: Danio rerio
• Alignment Length: 569
• Identity: 120/569 - (21%)
• Similarity: 181/569 - (31%)
• Gaps: 256/569 - (44%)

  Fly    39 MGAGASATLSVELCLVCGDRASGRHYGAISCEGCKGFFKRSIRKQLGYQCRGAMNCEVTKHHRNR 103
            :|||.       ||.:|||||:|:||||.||:||||||:||:||...|.||....|.|.|..||:
Zfish    56 LGAGT-------LCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFNRQCIVDKDKRNQ 113

  Fly   104 CQFCRLQKCLASGMR-----SDSVQHERKPIVDRKEGIIAAAGSSSTSGGGNGSSTYLSGKSGYQ 163
            |::|||:||..:||:     |.:||:||..|..|:                   |:|
Zfish   114 CRYCRLKKCFRAGMKKEVISSSAVQNERDRISTRR-------------------SSY-------- 151

  Fly   164 QGRGKGHSVKAESAATPPVHSAPATAFNLNENIFPMGLNFAELTQTLMFATQQQQQQQQQHQQSG 228
                                                                             
Zfish   152 ----------------------------------------------------------------- 151

  Fly   229 SYSPDIPKADPEDDEDDSMDNSSTLCLQLLANSASNNNSQHLNFNAGEVPTALPTTSTMGLIQSS 293
                          ||.|                                  ||  |...|||:.
Zfish   152 --------------EDSS----------------------------------LP--SINALIQAD 166

  Fly   294 LDMRVIHKGLQILQPIQNQLERNGNLSVKPECDSEAEDSGTEDAVDAELEHMELDFECGGNRSGG 358
            :..|.|.....||         ||::..|...
Zfish   167 VLSRQISSPGPIL---------NGDIRTKKVA--------------------------------- 189

  Fly   359 SDFAINEAVFEQDLLTDVQCAFHVQPPTLVHSYLNIHYVCETGSRIIFLTIHTLRKVPVFEQLEA 423
                   |:.:                           |||:..:.:.:.:...:.:|.|..|..
Zfish   190 -------AIMD---------------------------VCESMKQQLLVLVEWAKYIPAFCDLPL 220

  Fly   424 HTQVKLLRGVWPALMAIALAQCQGQLSVPTIIGQFIQSTRQLADIDKIEP-----LKISKMANLT 483
            ..||.|||......:.:..|:.........::|.           |.|.|     |::|::|  .
Zfish   221 DDQVALLRAHAGEHLLLGAAKRSMMYKDILLLGN-----------DHIIPRNCPELEVSRVA--V 272

  Fly   484 RTLHDFVQELQSLDVTDMEFGLLRLILLFNPT---LLQQRKERSLRGYVRRVQLYALSSLRRQGG 545
            |.|.:.|...|.|.:.|.|:..|:.|:.|:|.   |....|.:.:| |..:|.|....:.|:...
Zfish   273 RILDELVLPFQDLQIDDNEYACLKAIVFFDPDAKGLSDPSKIKRMR-YQVQVSLEDYINDRQYDS 336

  Fly   546 IGGGEERFNVLVARLLPLSSLDAEAMEELFFANLVGQMQMDALIPFILM 594
            .|    ||..|:..|..|.|:..:.:|::.|..|.|..::|.|:..:|:
Zfish   337 RG----RFGELLLLLPTLQSITWQMIEQIQFVKLFGMAKIDNLLQEMLL 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr78	NP_001189151.1	NR_DBD_TR2_like	47..133	CDD:143525	46/90 (51%)
		NR_LBD_TR2_like	372..595	CDD:132750	51/231 (22%)
hnf4a	XP_021325423.1	NR_DBD_HNF4A	62..142	CDD:143518	43/79 (54%)
		NR_LBD_HNF4_like	158..379	CDD:132729	62/314 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577478
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840