Protein Alignment Hr78 and usp

DIOPT Version :9

• Sequence 1: NP_001189151.1
• Gene: Hr78 / 40378
• FlyBaseID: FBgn0015239
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001259168.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Alignment Length: 629
• Identity: 143/629 - (22%)
• Similarity: 210/629 - (33%)
• Gaps: 240/629 - (38%)

  Fly    16 RAMPLI----GGGSASGGTPLPGGG----VGMGAGASATLSVE--------------LCLVCGDR 58
            :||.::    |..|||......|..    ....||.||..:|:              ||.:||||
  Fly    46 QAMSMVHVLPGSNSASSNNNSAGDAQMAQAPNSAGGSAAAAVQQQYPPNHPLSGSKHLCSICGDR 110

  Fly    59 ASGRHYGAISCEGCKGFFKRSIRKQLGYQCRGAMNCEVTKHHRNRCQFCRLQKCLASGMRSDSVQ 123
            |||:|||..|||||||||||::||.|.|.||...||.:.|..|||||:||.||||..||:.::||
  Fly   111 ASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKREAVQ 175

  Fly   124 HERKPIVDRKEGIIAAAGSSSTSGGGNGSSTYLSGKSGYQQGRGKGHSVKAESAATPPVHSAPAT 188
            .|      |:.|...|||..|.||||:.....:.|.|  .||.|.|..|..
  Fly   176 EE------RQRGARNAAGRLSASGGGSSGPGSVGGSS--SQGGGGGGGVSG-------------- 218

  Fly   189 AFNLNENIFPMGLNFAELTQTLMFATQQQQQQQQQHQQSGSYSPDIPKADPEDDEDDSMDNSSTL 253
                     .||                          ||:.|            ||.|.||.:
  Fly   219 ---------GMG--------------------------SGNGS------------DDFMTNSVS- 235

  Fly   254 CLQLLANSASNNNSQHLNFNAGEVPTALPTTSTMGLIQSSLDMRVIHKGLQILQPIQNQLERNGN 318
                                                                             
  Fly   236 ----------------------------------------------------------------- 235

  Fly   319 LSVKPECDSEAEDSGTEDAVDAELEHMELDFECGGNRSGGSDFAINEAVFEQDLLTDVQCA---- 379
                                                    .||:| |.:.|.:...:.||.
  Fly   236 ----------------------------------------RDFSI-ERIIEAEQRAETQCGDRAL 259

  Fly   380 --FHVQP-PTLVHSYLN-IHYVCETGSRIIFLTIHTLRKVPVFEQLEAHTQVKLLRGVWPALMAI 440
              ..|.| .|:...|.. :..:|:..::.:|..:...|.:|.|.|:....||.||:..|..|:..
  Fly   260 TFLRVGPYSTVQPDYKGAVSALCQVVNKQLFQMVEYARMMPHFAQVPLDDQVILLKAAWIELLIA 324

  Fly   441 ALAQCQGQLSVPTI--------------IGQFIQST----------RQLADIDKIEPLKISKMAN 481
            .:|.|    |:.::              .|.|.:.:          .|.....:...:|....|.
  Fly   325 NVAWC----SIVSLDDGGAGGGGGGLGHDGSFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAI 385

  Fly   482 LTRTLHDFVQELQSLDVTDMEFGLLRLILLFNPTL--LQQRKERSLRGYVRRVQLYALSSLRRQG 544
            ..|.|.:...:::.|::...|...|:.|:|:||.:  ::.|.|..:    .|.::||......:.
  Fly   386 FDRILSELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEIEM----CREKVYACLDEHCRL 446

  Fly   545 GIGGGEERFNVLVARLLPLSSLDAEAMEELFFANLVGQMQMDAL 588
            ...|.:.||..|:.||..|.|:..:..:.||...:.....::.|
  Fly   447 EHPGDDGRFAQLLLRLPALRSISLKCQDHLFLFRITSDRPLEEL 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr78	NP_001189151.1	NR_DBD_TR2_like	47..133	CDD:143525	49/99 (49%)
		NR_LBD_TR2_like	372..595	CDD:132750	51/251 (20%)
usp	NP_001259168.1	NR_DBD_RXR	102..178	CDD:143514	48/81 (59%)
		NR_LBD_RXR_like	237..480	CDD:132741	55/251 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444771
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24083
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940