Protein Alignment Hr78 and rxrbb

DIOPT Version :9

• Sequence 1: NP_001189151.1
• Gene: Hr78 / 40378
• FlyBaseID: FBgn0015239
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_571313.1
• Gene: rxrbb / 30486
• ZFINID: ZDB-GENE-990415-242
• Length: 422
• Species: Danio rerio
• Alignment Length: 601
• Identity: 129/601 - (21%)
• Similarity: 190/601 - (31%)
• Gaps: 272/601 - (45%)

  Fly    12 SEENRAMPLIGGGSASGGTPLPGGGVGMGAGASATLSVE-LCLVCGDRASGRHYGAISCEGCKGF 75
            |..:...|..|..|.||..|:              ||.: :|.:||||:||:|||..||||||||
Zfish    63 SSSDDVKPPFGLKSVSGSGPM--------------LSQKRMCAICGDRSSGKHYGVYSCEGCKGF 113

  Fly    76 FKRSIRKQLGYQCRGAMNCEVTKHHRNRCQFCRLQKCLASGMRSDSVQHERKPIVDRKEGIIAAA 140
            |||::||.|.|.||....|.|.|..|||||:||.|||||.||:.::||.||
Zfish   114 FKRTVRKDLSYTCRDNKECLVDKRQRNRCQYCRYQKCLAMGMKREAVQEER-------------- 164

  Fly   141 GSSSTSGGGNGSSTYLSGKSGYQQGRGKGHSVKAESAATPPVHSAPATAFNLNENIFPMGLNFAE 205
                                                                             
Zfish   165 ----------------------------------------------------------------- 164

  Fly   206 LTQTLMFATQQQQQQQQQHQQSGSYSPDIPKADPEDDEDDSMDNSSTLCLQLLANSASNNNSQHL 270
                           |:..::.|.|
Zfish   165 ---------------QKNKERDGDY---------------------------------------- 174

  Fly   271 NFNAGEVPTALPTTSTMGLIQSSLDMRVIHKGLQILQPIQNQLERNGNLSVKPECDSEA-EDSGT 334
                                                                 ||.|.| |:...
Zfish   175 -----------------------------------------------------ECSSSANEEMPV 186

  Fly   335 EDAVDAE--LEH-MELDFECGGNRSGGSDFAINEAVFEQDLLTDVQCAFHVQPPTLVHSYLNIHY 396
            |..::||  :|| .:|..:..|:              ..|.:|:
Zfish   187 EKILEAETAVEHRTDLHSDATGS--------------PNDPVTN--------------------- 216

  Fly   397 VCETGSRIIFLTIHTLRKVPVFEQLEAHTQVKLLRGVWPALMAIALA----QCQGQLSVPTIIGQ 457
            :|:...:.:|..:...::||.|..:....||.|||..|..|:..|.:    ..:.::.:.|.:..
Zfish   217 ICQAADKQLFTLVEWAKRVPHFSDVPLDDQVILLRAGWNELLIAAFSHRSISVKDEILLATGLHV 281

  Fly   458 FIQSTRQL---ADIDKIEPLKISKMANLTRTLHDFVQELQSLDVTDMEFGLLRLILLFNP----- 514
            ..:||..|   |..|:.........|...|.|.:.|.:::.:.:...|.|.||.|:||||
Zfish   282 PKESTHNLGVEAFFDRESSHSAEVGALFDRVLTELVCKMRDMQMDKTELGCLRAIVLFNPDAKGL 346

  Fly   515 ------TLLQQRKERSLRGYVRRVQLYALSSLRRQGGIGGGEERFNVLVARLLPLSSLDAEAMEE 573
                  .||:::...||..|.:  |.|.    .:||       ||..|:.||..|.|:..:.:|.
Zfish   347 TSSSEVELLREKVYASLESYCK--QKYP----DQQG-------RFAKLLLRLPALRSIGLKCLEH 398

  Fly   574 LFFANLVGQMQMDALI 589
            |||..|:|...:|..:
Zfish   399 LFFFKLIGNTPIDTFL 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr78	NP_001189151.1	NR_DBD_TR2_like	47..133	CDD:143525	50/86 (58%)
		NR_LBD_TR2_like	372..595	CDD:132750	56/236 (24%)
rxrbb	NP_571313.1	Modulating. /evidence=ECO:0000250	1..89		9/39 (23%)
		Nuc_recep-AF1	<21..77	CDD:288658	3/13 (23%)
		NR_DBD_RXR	89..164	CDD:143514	46/74 (62%)
		Hinge. /evidence=ECO:0000250	156..178		9/208 (4%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..182		10/207 (5%)
		NR_LBD_RXR_like	183..403	CDD:132741	61/267 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577483
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840