Protein Alignment Hr78 and nhr-35

DIOPT Version :9

• Sequence 1: NP_001189151.1
• Gene: Hr78 / 40378
• FlyBaseID: FBgn0015239
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001024365.1
• Gene: nhr-35 / 180725
• WormBaseID: WBGene00003628
• Length: 542
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 116/595 - (19%)
• Similarity: 180/595 - (30%)
• Gaps: 273/595 - (45%)

  Fly    51 LCLVCGDRASGRHYGAISCEGCKGFFKRSIRKQLGYQCRGAMNCEVTKHHRNRCQFCRLQKCLAS 115
            :|.:|.|.|:|||||||:|.||||||:|::|:...|.||....||:.||:|..|::||..||::|
 Worm    76 ICHICSDVATGRHYGAIACNGCKGFFRRTVRRNYEYHCRFESKCEIDKHNRAVCRYCRFMKCISS 140

  Fly   116 GMRSDSVQHERKPIVDRKEGIIAAAGSSSTSGGGNGSSTYLSGKSGYQQGRGKGHSVKAESAATP 180
            |||.|.||.||..|..|
 Worm   141 GMRDDQVQSERDVIGKR------------------------------------------------ 157

  Fly   181 PVHSAPATAFNLNENIFPMGLNFAELTQTLMFATQQQQQQQQQHQQSGSYSPDIPKADPEDDEDD 245
                                                                            :
 Worm   158 ----------------------------------------------------------------E 158

  Fly   246 SMDNSSTLCLQLLANSASNNNSQHLNFNAGEVPTALPTTS---TMGLIQSSLDMRVIHKGLQILQ 307
            ..||..|.|                     :.||  |.||   ||..::...|        |:|:
 Worm   159 KKDNMKTYC---------------------QDPT--PRTSPELTMSPVEDEYD--------QLLE 192

  Fly   308 PIQNQLERNGNLSVKPECDSEAEDSGTEDAVDAELEHMELDFECGGNRSGGSDFAINEAVFEQDL 372
            .:               ..||.......|.|..:..::|...: ..||...:|        ....
 Worm   193 SL---------------LKSEMTIQSLRDTVITQTGNVEYTTK-SKNRLSHTD--------RTAT 233

  Fly   373 LTDVQCAFHVQPPTLVHSYLNIHYVCETGSRIIFLTIHTLRKVPVFEQLEAHTQVKLLRGVWPAL 437
            |.||..:.|.|                     :.|.|...:.:|.|:||....|..||:......
 Worm   234 LNDVLKSMHSQ---------------------LLLVIEWAKTLPEFKQLSGADQAVLLKNFAGQH 277

  Fly   438 MAIALA----------QCQGQLSVPT-----------IIGQFIQSTRQLADIDKIEPLKISKMAN 481
            :.:.:|          :....|.:|.           :.|.:::...::.| ..:||::..|:.|
 Worm   278 VTLCVAYRSVGANDALKLLNDLYIPRASKTTPHLKEYVDGFYLRDCEKVMD-QLVEPMRFLKLDN 341

  Fly   482 LTRTLHDFVQELQSLDVTDMEFGLLRLILLFNPT-----------LLQQRKE--RSLRGYVR--- 530
                               .||..|:..:||||.           :|..|::  .:...|||
 Worm   342 -------------------KEFVALKACVLFNPVAPGLSNHAVNLVLNARRKIFAAFEKYVRVNK 387

  Fly   531 -----RVQLYALSSLRRQGGIGGGEERFNVLVARLLPLSSLDAEAMEELFFANLVGQMQMDALIP 590
                 ||                |:..|.:|.    |||.|.....|::.|..:.|..::|.|:.
 Worm   388 PLETTRV----------------GDLTFFILT----PLSVLSKSISEDIMFTKVSGVARIDVLME 432

  Fly   591 FILMTSNTSG 600
            .:::.....|
 Worm   433 ELILAETDYG 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr78	NP_001189151.1	NR_DBD_TR2_like	47..133	CDD:143525	43/81 (53%)
		NR_LBD_TR2_like	372..595	CDD:132750	49/264 (19%)
nhr-35	NP_001024365.1	NR_DBD_HNF4A	77..152	CDD:143518	41/74 (55%)
		NR_LBD	230..434	CDD:299703	49/264 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910