Protein Alignment Hr78 and rxra

DIOPT Version :10

• Sequence 1: NP_730636.1
• Gene: Hr78 / 40378
• FlyBaseID: FBgn0015239
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_012824678.1
• Gene: rxra / 100487877
• XenbaseID: XB-GENE-478718
• Length: 498
• Species: Xenopus tropicalis
• Alignment Length: 598
• Identity: 132/598 - (22%)
• Similarity: 203/598 - (33%)
• Gaps: 251/598 - (41%)

  Fly    19 PLIGGGSASGGTPLPG-GGV----GMGAGASATLSVELCLVCGDRASGRHYGAISCEGCKGFFKR 78
            |:....|.....|.|| .|:    ...:|..|:.:..:|.:||||:||:|||..|||||||||||
 Frog   114 PMNSVSSTEDIKPPPGINGILKVPAHPSGPMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKR 178

  Fly    79 SIRKQLGYQCRGAMNCEVTKHHRNRCQFCRLQKCLASGMRSDSVQHERKPIVDRKEGIIAAAGSS 143
            ::||.|.|.||.:.:|.:.|..|||||:||.|||||.||:.:.::|.
 Frog   179 TVRKDLTYTCRDSKDCMIDKRQRNRCQYCRYQKCLAMGMKREGMEHH------------------ 225

  Fly   144 STSGGGNGSSTYLSGKSGYQQGRGKGHSVKAESAATPPVHSAPATAFNLNENIFPMGLNFAELTQ 208
                                                |..||.....
 Frog   226 ------------------------------------PSQHSRDLRC------------------- 235

  Fly   209 TLMFATQQQQQQQQQHQQSGSYSPDIPKADPEDDEDDSMDNSSTLCLQLLANSASNNNSQHLNFN 273
                   |.:|..|:.:|.|           ::..::.:::||:      ||.
 Frog   236 -------QAEQAVQEERQRG-----------KERNENEVESSSS------ANE------------ 264

  Fly   274 AGEVPTALPTTSTMGLIQSSLDMRVIHKGLQILQPIQNQLERNGNLSVKPECDSEAEDSGTEDAV 338
                                 ||           |::..|:  ...:|:|:         ||..:
 Frog   265 ---------------------DM-----------PVEKILD--AEHAVEPK---------TETYI 286

  Fly   339 DAELEHMELDFECGGNRSGGSDFAINEAVFEQDLLTDVQCAFHVQPPTLVHSYLNIHYVCETGSR 403
            :|.:         |...:..||...|                                :|:...:
 Frog   287 EANM---------GLAPNSPSDPVTN--------------------------------ICQAADK 310

  Fly   404 IIFLTIHTLRKVPVFEQLEAHTQVKLLRGVWPALMAIALAQCQGQLSVPTIIGQFIQSTRQLADI 468
            .:|..:...:::|.|.:|....||.|||..|..|                :|..|  |.|.:|..
 Frog   311 QLFTLVEWAKRIPHFSELPLDDQVILLRAGWNEL----------------LIASF--SHRSIAVK 357

  Fly   469 DKI---EPLKISKM--------ANLTRTLHDFVQELQSLDVTDMEFGLLRLILLFNP-------- 514
            |.|   ..|.:.:.        |...|.|.:.|.:::.:.:...|.|.||.|:||||
 Frog   358 DGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNP 422

  Fly   515 ---TLLQQRKERSLRGYVRRVQLYALSSLRRQGGIGGGEERFNVLVARLLPLSSLDAEAMEELFF 576
               ..|:::...||..|.:  |.|.     .|.|      ||..|:.||..|.|:..:.:|.|||
 Frog   423 SEVEALREKVYASLEAYCK--QKYP-----EQPG------RFAKLLLRLPALRSIGLKCLEHLFF 474

  Fly   577 ANLVGQMQMDALI 589
            ..|:|...:|..:
 Frog   475 FKLIGDTPIDTFL 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr78	NP_730636.1	NR_DBD_TR2_like	47..133	CDD:143525	44/85 (52%)
		NR_LBD_TR2_like	372..595	CDD:132750	55/240 (23%)
rxra	XP_012824678.1	Nuc_recep-AF1	37..144	CDD:463363	7/29 (24%)
		NR_DBD_RXR	150..245	CDD:143514	50/174 (29%)
		NR_LBD_RXR_like	265..476	CDD:132741	65/304 (21%)