Protein Alignment Neu2 and znf973

DIOPT Version :10

• Sequence 1: NP_649316.1
• Gene: Neu2 / 40375
• FlyBaseID: FBgn0037085
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001104625.1
• Gene: znf973 / 557295
• ZFINID: ZDB-GENE-080218-9
• Length: 345
• Species: Danio rerio
• Alignment Length: 354
• Identity: 117/354 - (33%)
• Similarity: 172/354 - (48%)
• Gaps: 52/354 - (14%)

  Fly    43 EDAQNAFDIIETYERSHQFYRFLKDVREEESENDG---------SGCSE--EVEAAERDLQDGAD 96
            ||.|...|:||..|.|.:....:|...:...:.||         ..|::  ::.|::..|:
Zfish    22 EDLQEQTDLIEEKEGSKEEEHHVKIEEKTHLQTDGILKRRDKNSFTCTQCGKILASKSKLK---- 82

  Fly    97 DVDSGNEPDINECDIKAKEKPGFSCSHCPKSFQVKSNLKVHMRSHTGERPFTCSLCPKSFGYSSG 161
                      ....|...||| |:|:.|.|||.:.|:|.:|||.||||:|:||:.|.|||.:.|.
Zfish    83 ----------IHMSIHTGEKP-FTCTQCGKSFSLSSSLNLHMRIHTGEKPYTCTQCGKSFSHLSP 136

  Fly   162 LQNHMRTHTGERPFQCSHCPRSFTAGHHLKAHIQMHERRGSLRCPYCQKCFLTSLILKQHLATHT 226
            |..|||.||||:||.|:.|.:||:....|..|:::|.......|..|.|.|..|..|.:|:..||
Zfish   137 LNKHMRIHTGEKPFTCTQCGKSFSLSTSLNLHMRIHTGEKPFTCTRCGKSFNCSSNLSKHMMIHT 201

  Fly   227 DETQFKCSQCSKSFQVEHELWMHMRVHQ-ERLFTCGHCSKDFALHAYLKRHLSRNARCSQSSKAS 290
            .:..|.|:||.|||::...|.:|||:|. |:.|||..|...|                ||||..:
Zfish   202 GKKPFTCTQCEKSFRISSSLNLHMRIHTGEKPFTCTQCGNSF----------------SQSSSLN 250

  Fly   291 AHKTLGHS--KALKCGKCPKTFTDRSALSTHLKSHTKNKPLLEGPCKSSGSKPAHSNAQ------ 347
            .|..: |:  |...|.:|.|:|.....|:.|::.||..||.....|:.|.:..:|.|..
Zfish   251 KHMRI-HTGEKPFTCTQCVKSFNRSEHLNLHMRIHTGEKPFTCTECEKSFTCSSHLNRHMRKHTG 314

  Fly   348 RKPFKCSSCPRTFSRKSALLTHLQTHTGK 376
            .||:.|:.|.:.||:.|.|..|:.:|.|:
Zfish   315 EKPYACTQCGKIFSQSSRLNLHMVSHNGE 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Neu2	NP_649316.1	zf-AD	1..63	CDD:462262	8/19 (42%)
		COG5048	<119..241	CDD:227381	55/121 (45%)
		C2H2 Zn finger	121..141	CDD:275368	10/19 (53%)
		zf-H2C2_2	133..156	CDD:463886	13/22 (59%)
		C2H2 Zn finger	149..169	CDD:275368	10/19 (53%)
		zf-H2C2_2	162..185	CDD:463886	13/22 (59%)
		C2H2 Zn finger	177..197	CDD:275368	6/19 (32%)
		C2H2 Zn finger	205..225	CDD:275368	7/19 (37%)
		zf-C2H2_8	206..286	CDD:464935	27/80 (34%)
		C2H2 Zn finger	233..253	CDD:275368	10/19 (53%)
		C2H2 Zn finger	260..297	CDD:275368	8/36 (22%)
		C2H2 Zn finger	303..323	CDD:275368	6/19 (32%)
		C2H2 Zn finger	353..373	CDD:275368	7/19 (37%)
znf973	NP_001104625.1	C2H2 Zn finger	68..88	CDD:275368	3/33 (9%)
		C2H2 Zn finger	96..116	CDD:275368	10/19 (53%)
		COG5048	120..>337	CDD:227381	81/233 (35%)
		C2H2 Zn finger	124..144	CDD:275368	10/19 (53%)
		C2H2 Zn finger	152..172	CDD:275368	6/19 (32%)
		C2H2 Zn finger	180..200	CDD:275368	7/19 (37%)
		C2H2 Zn finger	208..228	CDD:275368	10/19 (53%)
		C2H2 Zn finger	236..256	CDD:275368	8/36 (22%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-H2C2_2	276..301	CDD:463886	8/24 (33%)
		C2H2 Zn finger	292..312	CDD:275368	4/19 (21%)
		zf-H2C2_2	304..329	CDD:463886	7/24 (29%)
		C2H2 Zn finger	320..340	CDD:275368	7/19 (37%)