DRSC/TRiP Functional Genomics Resources

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Protein Alignment Neu2 and CG7386

DIOPT Version :9

Sequence 1:NP_649316.1 Gene:Neu2 / 40375 FlyBaseID:FBgn0037085 Length:382 Species:Drosophila melanogaster
Sequence 2:NP_648036.1 Gene:CG7386 / 38719 FlyBaseID:FBgn0035691 Length:662 Species:Drosophila melanogaster


Alignment Length:601 Identity:115/601 - (19%)
Similarity:168/601 - (27%) Gaps:271/601 - (45%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 CTGWQVEKHDPLSNTICKSCLEDAQNAFDIIETYERSHQFYRFLKDVRE--EESENDGSGCSEEV 84
            ||.:..:::|.....:|..|.....:..|..|....|      :|.::|  ....|...|..|.:
  Fly    39 CTSFDADQNDGFPRNLCTQCFTKLNDLHDFRELCAES------IKRLKEMMTSQRNMPMGVFESI 97

  Fly    85 ----EAAER---------------DLQDGADDV----------------DSGNE----PDINECD 110
                ||.||               ::.|..:||                |...|    .:.|..:
  Fly    98 ADDSEAPERPEEPASFDPLLNNKLEMIDNEEDVFKLLEKVDKELEEHSRDQSEEHFSSAEHNGLE 162

  Fly   111 IKAKEKPGF------------------------SCSHCPKSFQVKSNLKVHMRSHTGERPFTC-- 149
            .:.||..||                        |||.|.:.|:.:|..:.||:.|....||.|  
  Fly   163 EEKKESEGFNSDDEQAMGQRRIANDKRKLFRLMSCSICQQKFKKQSKFEEHMKHHNDLLPFQCQE 227

  Fly   150 SLCPKSFGYSSGL---------------------------------------------------- 162
            ..|.|.|..:..|                                                    
  Fly   228 ESCRKGFTTAGALRLHVDYAHSKKEDTVPCTVEGCQLVFSRLRLLTIHLKKVHNQARVIAPRGEQ 292

  Fly   163 ---------------QNHMRTHTGER-PFQCSHCPRSFTAGHHLKAHIQMHERRGSLRCPYCQKC 211
                           :.||.|||||. |:.|:.|.:.|.....||.|:..|....:..|.||...
  Fly   293 SCKECGVVFRCPVAMKKHMYTHTGEELPYPCTICGKGFYINSALKNHLLRHAGIKNYVCQYCGVR 357

  Fly   212 FLTSLILKQHLATHTDETQFKCSQCSKSFQVEHELWMHMRVHQERL--FTCGHCSKDFALHAYLK 274
            ..|.....:|:..||...||||..|..:...:..|..|:::..|::  |.|.:|.|.|       
  Fly   358 KTTRQEWSKHILIHTQRNQFKCRICDYATHTKRVLESHVKIVHEKIRNFACQYCGKTF------- 415

  Fly   275 RHLSRNARCSQSSKASAHK--TLGHS--KALKCGKCPKTFTDRSALSTHLKSHTKN--------- 326
                        .||.|.|  .:.|:  |..:|..|.|.|....:|:.|||.|.|:         
  Fly   416 ------------GKAYACKIHEMAHTGEKRCECKVCDKKFLHSESLNNHLKIHEKSVERALETYK 468

  Fly   327 -------------------------------KP---------LLEGPC----------------- 334
                                           .|         ||.|..                 
  Fly   469 QVQVNGDASDTQVDSHQLLKVYAESVASIPKNPRRVEQVDVALLAGTAVNPTDEIQFVQKEGMYL 533

  Fly   335 --------KSSGSKPAH--------------------SNAQ-----------RKPFKCSSCPRTF 360
                    ||.|:...|                    :|:|           .|||:|.:|...|
  Fly   534 CPSCSQGFKSIGNMKRHYKSVHEKVKDFECRFCSRRFANSQSVKQHEWIHTGEKPFECKTCGNRF 598

  Fly   361 SRKSALLTHLQTHTGK 376
            .:.:||:.|.:.|..|
  Fly   599 RQVAALIRHQKVHDEK 614

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Neu2NP_649316.1 zf-AD 1..63 CDD:285071 8/40 (20%)
COG5048 <119..241 CDD:227381 44/215 (20%)
C2H2 Zn finger 121..141 CDD:275368 7/19 (37%)
zf-H2C2_2 133..158 CDD:290200 9/26 (35%)
C2H2 Zn finger 149..169 CDD:275368 7/88 (8%)
zf-H2C2_2 162..185 CDD:290200 11/90 (12%)
C2H2 Zn finger 177..197 CDD:275368 6/19 (32%)
C2H2 Zn finger 205..225 CDD:275368 5/19 (26%)
zf-C2H2_8 206..286 CDD:292531 19/81 (23%)
C2H2 Zn finger 233..253 CDD:275368 4/19 (21%)
C2H2 Zn finger 260..297 CDD:275368 8/38 (21%)
C2H2 Zn finger 303..323 CDD:275368 8/19 (42%)
C2H2 Zn finger 353..373 CDD:275368 6/19 (32%)
CG7386NP_648036.1 zf-AD 10..81 CDD:214871 9/47 (19%)
C2H2 Zn finger 197..217 CDD:275368 7/19 (37%)
C2H2 Zn finger 294..314 CDD:275368 2/19 (11%)
C2H2 Zn finger 323..343 CDD:275368 6/19 (32%)
C2H2 Zn finger 351..371 CDD:275368 5/19 (26%)
C2H2 Zn finger 379..400 CDD:275368 4/20 (20%)
C2H2 Zn finger 408..428 CDD:275368 8/38 (21%)
C2H2 Zn finger 436..456 CDD:275368 8/19 (42%)
C2H2 Zn finger 534..555 CDD:275368 4/20 (20%)
C2H2 Zn finger 563..583 CDD:275368 2/19 (11%)
zf-H2C2_2 575..600 CDD:290200 6/24 (25%)
C2H2 Zn finger 591..611 CDD:275368 6/19 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45446568
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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