DRSC/TRiP Functional Genomics Resources

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Protein Alignment Neu2 and CG43347

DIOPT Version :9

Sequence 1:NP_649316.1 Gene:Neu2 / 40375 FlyBaseID:FBgn0037085 Length:382 Species:Drosophila melanogaster
Sequence 2:NP_001138185.2 Gene:CG43347 / 31991 FlyBaseID:FBgn0263072 Length:2684 Species:Drosophila melanogaster


Alignment Length:363 Identity:81/363 - (22%)
Similarity:135/363 - (37%) Gaps:105/363 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 ICKSCLEDAQNAFDIIETYERSHQFYRFLKDV--REEESENDGSGCSEEVEAAERDLQDG----- 94
            |.:.|...|..::.:......:..:.||::..  .||.:.|..|...:....:.|||::|     
  Fly  1081 IFEMCEAGADKSYLLCCDNPNASNWLRFVRPAPSYEERNVNLVSIDRQAYFVSCRDLRNGMELLY 1145

  Fly    95 -ADDVDS------GNEPDINECDIKAKEKPGFSCSHCPKSFQVKSNLKVHMRSHTGERPFTCSLC 152
             :||.::      ..:.:...|::|. |.|.:..:||........:|.:        |.:.|.:|
  Fly  1146 WSDDCNTMWRKKHTEKTNCGGCNLKF-EHPLYYRTHCSVFHDPSMSLTI--------RKYHCKVC 1201

  Fly   153 PKSFGYSSGLQNHMRTHTGERPFQCSHCPRSFTAGHHLKAHIQMHERRGSLRCPYCQKCFLTSLI 217
            .:..   .|..|.|: |..|:                       |:.:|:.:|.:|.|.||....
  Fly  1202 GEPV---LGKDNIMK-HAAEK-----------------------HDGKGAYQCQFCSKFFLRLNY 1239

  Fly   218 LKQH----LATHTDETQFKCSQCSKSFQVEHELWMHM-RVHQE-----RLFTCGHCSKDFALHAY 272
            |:.|    .|::.:.::..|..|.:.|....:|..|: |:|.:     |.|.|..|||.....|.
  Fly  1240 LEMHRTYGCASNPNRSRPVCDFCGRKFCQPQKLKAHIKRMHSDMAEVLRDFQCKLCSKLLGSRAA 1304

  Fly   273 LKRHL----SRNARCSQSSKASAHKTLGHSKALKCGKCPKTFTDRSALSTHLKSHTKNKPLLEGP 333
            |:||.    |||                 |..:.|.:|.|.|.:||.|..|:.:|          
  Fly  1305 LQRHSKEVHSRN-----------------STVVSCPRCQKLFQNRSNLKIHMLTH---------- 1342

  Fly   334 CKSSGSKPAHSNAQRKPFKCS--SCPRTFSRKSALLTH 369
               ||.         :||||:  .|...|:.|..|..|
  Fly  1343 ---SGV---------RPFKCAEPECNAAFTTKQCLQFH 1368

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Neu2NP_649316.1 zf-AD 1..63 CDD:285071 3/25 (12%)
COG5048 <119..241 CDD:227381 23/125 (18%)
C2H2 Zn finger 121..141 CDD:275368 3/19 (16%)
zf-H2C2_2 133..158 CDD:290200 4/24 (17%)
C2H2 Zn finger 149..169 CDD:275368 5/19 (26%)
zf-H2C2_2 162..185 CDD:290200 4/22 (18%)
C2H2 Zn finger 177..197 CDD:275368 0/19 (0%)
C2H2 Zn finger 205..225 CDD:275368 8/23 (35%)
zf-C2H2_8 206..286 CDD:292531 27/93 (29%)
C2H2 Zn finger 233..253 CDD:275368 6/20 (30%)
C2H2 Zn finger 260..297 CDD:275368 11/40 (28%)
C2H2 Zn finger 303..323 CDD:275368 8/19 (42%)
C2H2 Zn finger 353..373 CDD:275368 6/19 (32%)
CG43347NP_001138185.2 NR_DBD_like 1198..>1268 CDD:295381 20/96 (21%)
C2H2 Zn finger 1198..1219 CDD:275368 7/47 (15%)
C2H2 Zn finger 1227..1255 CDD:275368 8/27 (30%)
C2H2 Zn finger 1259..1280 CDD:275368 6/20 (30%)
C2H2 Zn finger 1292..1313 CDD:275368 8/20 (40%)
C2H2 Zn finger 1322..1342 CDD:275368 8/19 (42%)
zf-H2C2_2 1334..1361 CDD:290200 11/48 (23%)
C2H2 Zn finger 1350..1373 CDD:275368 6/19 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24409
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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