DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Neu2 and LOC108184006

DIOPT Version :9

Sequence 1:	NP_649316.1	Gene:	Neu2 / 40375	FlyBaseID:	FBgn0037085	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	XP_017211284.1	Gene:	LOC108184006 / 108184006	-ID:	-	Length:	359	Species:	Danio rerio

Alignment Length:	381	Identity:	108/381 - (28%)
Similarity:	161/381 - (42%)	Gaps:	95/381 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 EDAQNAFDIIETYERSHQFYRFLKDVREEESENDGSGCSEEVEAAERDLQDGADDVDSGNEPDI- 106
            ||.|...|::...|.:||:                           .::::...|:.:..:|.:
Zfish    22 EDLQEQTDLMVLKEETHQW---------------------------NEMEEKHQDILTDEKPTLT 59

  Fly   107 -------------NECDIKAK---------------------EKPGFSCSHCPKSFQVKSNLKVH 137
                         ::|:..:|                     ||| .:|..|.|||....||.||
Zfish    60 KKTSSRGRPRKSKSKCNFSSKQRRKTFSQKPKLDVHMRVHTGEKP-CTCKQCGKSFYTIGNLTVH 123

  Fly   138 MRSHTGERPFTCSLCPKSFGYSSGLQNHMRTHTGERPFQCSHCPRSFTAGHHLKAHIQMHERRGS 202
            ||.||||:|:||..|.|||......:.|:|.||||||:.|..|.:||....:|..|:::|.....
Zfish   124 MRIHTGEKPYTCEQCGKSFFQKENFKTHIRIHTGERPYTCQQCGKSFYHAGNLIMHMRIHTEERP 188

  Fly   203 LRCPYCQKCFLTSLILKQHLATHTDETQFKCSQCSKSFQVEHELWMHMRVHQ-ERLFTCGHCSKD 266
            ..||.|.|.|..:..|:.|:.|||.|.:|.|:||.|||..:..|.:|||:|. |:.:||..|.|.
Zfish   189 YSCPQCGKSFKQNGNLEVHMRTHTGEKRFTCTQCGKSFVKKQNLDIHMRIHTGEKPYTCTECGKS 253

  Fly   267 FALHAYLKRHLSRNARCSQSSKASAHKTLGHSKALKCGKCPKTFTDRSALSTHLKSHTKNKPLLE 331
            |...:.||.|:               :|........|.:|.|:|:.:|:|..|:..||..   :.
Zfish   254 FTYKSTLKHHM---------------RTHTGENPFACAQCGKSFSTKSSLMNHMNGHTGT---IV 300

  Fly   332 GPCKSSGSK-----------PAHSNAQRKPFKCSSCPRTFSRKSALLTHLQTHTGK 376
            ..|...|.|           ..||....  |:||.|.:.|:.|.:|..||:.|..:
Zfish   301 FTCDQCGIKLTRKDYIRRHMKTHSREDH--FRCSECGKGFTHKRSLSAHLKLHNAE 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Neu2	NP_649316.1	zf-AD	1..63	CDD:285071	7/19 (37%)
		COG5048	<119..241	CDD:227381	54/121 (45%)
		C2H2 Zn finger	121..141	CDD:275368	11/19 (58%)
		zf-H2C2_2	133..158	CDD:290200	17/24 (71%)
		C2H2 Zn finger	149..169	CDD:275368	7/19 (37%)
		zf-H2C2_2	162..185	CDD:290200	11/22 (50%)
		C2H2 Zn finger	177..197	CDD:275368	6/19 (32%)
		C2H2 Zn finger	205..225	CDD:275368	7/19 (37%)
		zf-C2H2_8	206..286	CDD:292531	31/80 (39%)
		C2H2 Zn finger	233..253	CDD:275368	10/19 (53%)
		C2H2 Zn finger	260..297	CDD:275368	8/36 (22%)
		C2H2 Zn finger	303..323	CDD:275368	7/19 (37%)
		C2H2 Zn finger	353..373	CDD:275368	8/19 (42%)
LOC108184006	XP_017211284.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000