Protein Alignment Neu2 and si:ch211-226o13.2

DIOPT Version :10

• Sequence 1: NP_649316.1
• Gene: Neu2 / 40375
• FlyBaseID: FBgn0037085
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: XP_005161564.2
• Gene: si:ch211-226o13.2 / 100149306
• ZFINID: ZDB-GENE-110913-67
• Length: 359
• Species: Danio rerio
• Alignment Length: 376
• Identity: 113/376 - (30%)
• Similarity: 162/376 - (43%)
• Gaps: 85/376 - (22%)

  Fly    43 EDAQNAFDIIETYERSHQFYRFLKDVREEESENDGSGCSEEVEAAERDLQDGADD-------VDS 100
            ||.....|::...|.:||                   |: |:|...:|:.  ||:       ..|
Zfish    22 EDLLEQTDLMVLKEETHQ-------------------CN-EMEEKHQDIM--ADEKPTLTKKTSS 64

  Fly   101 GNEP--DINECDIKAK---------------------EKPGFSCSHCPKSFQVKSNLKVHMRSHT 142
            ...|  ..::|:..:|                     ||| .:|..|.|||....||.||||.||
Zfish    65 RGRPRKSKSKCNFSSKQRRKTFSQKPKLDVHMRVHTGEKP-CTCKQCGKSFYTIGNLTVHMRIHT 128

  Fly   143 GERPFTCSLCPKSFGYSSGLQNHMRTHTGERPFQCSHCPRSFTAGHHLKAHIQMHERRGSLRCPY 207
            ||:|:||..|.|||......:.|||.||||||:.|..|.:||....:|..|:::|.......||.
Zfish   129 GEKPYTCEQCGKSFCKKENFKTHMRIHTGERPYTCQQCGKSFYHAGNLIMHMRIHTEERPYSCPQ 193

  Fly   208 CQKCFLTSLILKQHLATHTDETQFKCSQCSKSFQVEHELWMHMRVHQ-ERLFTCGHCSKDFALHA 271
            |.|.|..:..|:.|:.|||.|.:|.|:||.|||..:..|.:|||:|. |:.:||..|.|.|...:
Zfish   194 CGKSFKQNGNLEVHMRTHTGEKRFTCTQCGKSFVKKQNLDIHMRIHTGEKPYTCTECGKSFTYKS 258

  Fly   272 YLKRHLSRNARCSQSSKASAHKTLGHSKALKCGKCPKTFTDRSALSTHLKSHTKNKPLLEGPCKS 336
            .||.|:               :|........|.:|.|:|:.:|:|..|:..||..   :...|..
Zfish   259 SLKHHM---------------RTHTGENPFACAQCGKSFSTKSSLMNHMNGHTGT---IVFTCDQ 305

  Fly   337 SGSK-----------PAHSNAQRKPFKCSSCPRTFSRKSALLTHLQTHTGK 376
            .|.|           ..||...|  |:|:...:.|:.|.:|..||:.|..:
Zfish   306 CGIKLTRKDYIRRHMKTHSRENR--FRCNEFGKGFTHKRSLSAHLKLHNAE 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Neu2	NP_649316.1	zf-AD	1..63	CDD:462262	6/19 (32%)
		COG5048	<119..241	CDD:227381	55/121 (45%)
		C2H2 Zn finger	121..141	CDD:275368	11/19 (58%)
		zf-H2C2_2	133..156	CDD:463886	15/22 (68%)
		C2H2 Zn finger	149..169	CDD:275368	8/19 (42%)
		zf-H2C2_2	162..185	CDD:463886	12/22 (55%)
		C2H2 Zn finger	177..197	CDD:275368	6/19 (32%)
		C2H2 Zn finger	205..225	CDD:275368	7/19 (37%)
		zf-C2H2_8	206..286	CDD:464935	31/80 (39%)
		C2H2 Zn finger	233..253	CDD:275368	10/19 (53%)
		C2H2 Zn finger	260..297	CDD:275368	8/36 (22%)
		C2H2 Zn finger	303..323	CDD:275368	7/19 (37%)
		C2H2 Zn finger	353..373	CDD:275368	6/19 (32%)
si:ch211-226o13.2	XP_005161564.2	C2H2 Zn finger	107..127	CDD:275368	11/19 (58%)
		COG5048	<131..291	CDD:227381	62/174 (36%)
		C2H2 Zn finger	135..155	CDD:275368	8/19 (42%)
		C2H2 Zn finger	163..183	CDD:275368	6/19 (32%)
		C2H2 Zn finger	191..211	CDD:275368	7/19 (37%)
		C2H2 Zn finger	219..239	CDD:275368	10/19 (53%)
		C2H2 Zn finger	247..267	CDD:275368	7/34 (21%)
		C2H2 Zn finger	275..295	CDD:275368	7/19 (37%)
		C2H2 Zn finger	303..323	CDD:275368	3/19 (16%)
		C2H2 Zn finger	331..351	CDD:275368	6/19 (32%)