Protein Alignment Neu2 and si:dkey-77f5.4

DIOPT Version :9

• Sequence 1: NP_649316.1
• Gene: Neu2 / 40375
• FlyBaseID: FBgn0037085
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: XP_009289663.1
• Gene: si:dkey-77f5.4 / 100147955
• ZFINID: ZDB-GENE-131121-70
• Length: 456
• Species: Danio rerio
• Alignment Length: 268
• Identity: 94/268 - (35%)
• Similarity: 134/268 - (50%)
• Gaps: 28/268 - (10%)

  Fly   119 FSCSHCPKSFQVKSNLKVHMRSHTGERPFTCSLCPKSFGYSSGLQNHMRTHTGERPFQCSHCPRS 183
            |:|..|.|.:.:|.||.:||||||.|:|:||..|.|||...:.|..|:|.||||:.|.|..|.:|
Zfish   148 FTCGQCGKGYSIKGNLDIHMRSHTEEKPYTCPHCGKSFVRKNTLHAHVRIHTGEKLFACPQCEKS 212

  Fly   184 FTAGHHLKAHIQMHERRGSLRCPYCQKCFLTSLILKQHLATHTDETQFKCSQCSKSFQVEHELWM 248
            |:....||.|:::|.......|..|.:.|.....|..|...||.|....|.||.|||..:|.|.:
Zfish   213 FSLQGQLKIHMRIHLETKPYSCSQCGRSFYDKKSLDVHTRIHTGEKPHTCPQCGKSFVHKHSLRI 277

  Fly   249 HMRVHQ-ERLFTCGHCSKDFALHAYLKRHLSRNARCSQSSKASAHKTLGHSKALKCGKCPKTFTD 312
            |.|.|. :||.:|..|.:.|::.|.||.|:               :|....|.:.||:|.|:|.:
Zfish   278 HSRFHSGQRLLSCQECGRCFSIKANLKAHM---------------RTHTGEKLVTCGQCGKSFAN 327

  Fly   313 RSALSTHLKSHTKNKPLLEGPCK-------SSGSKPAH--SNAQRKPFKCSSCPRTFSRKSALLT 368
            :|.|:||::.||..:|.:   ||       ..|:..||  ::...||:.|..|..||.....|..
Zfish   328 QSYLTTHMRIHTGERPFV---CKECGKGFHKRGNLTAHMRTHTGEKPYSCKICEETFRSTQTLKG 389

  Fly   369 HLQTHTGK 376
            |:..||.:
Zfish   390 HMSVHTAE 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Neu2	NP_649316.1	zf-AD	1..63	CDD:285071
		COG5048	<119..241	CDD:227381	50/121 (41%)
		C2H2 Zn finger	121..141	CDD:275368	9/19 (47%)
		zf-H2C2_2	133..158	CDD:290200	16/24 (67%)
		C2H2 Zn finger	149..169	CDD:275368	8/19 (42%)
		zf-H2C2_2	162..185	CDD:290200	11/22 (50%)
		C2H2 Zn finger	177..197	CDD:275368	7/19 (37%)
		C2H2 Zn finger	205..225	CDD:275368	5/19 (26%)
		zf-C2H2_8	206..286	CDD:292531	27/80 (34%)
		C2H2 Zn finger	233..253	CDD:275368	10/19 (53%)
		C2H2 Zn finger	260..297	CDD:275368	8/36 (22%)
		C2H2 Zn finger	303..323	CDD:275368	9/19 (47%)
		C2H2 Zn finger	353..373	CDD:275368	6/19 (32%)
si:dkey-77f5.4	XP_009289663.1	COG5048	82..441	CDD:227381	94/268 (35%)
		C2H2 Zn finger	94..114	CDD:275368
		zf-H2C2_2	106..131	CDD:290200
		C2H2 Zn finger	122..142	CDD:275368
		C2H2 Zn finger	150..170	CDD:275368	9/19 (47%)
		zf-H2C2_2	162..187	CDD:290200	16/24 (67%)
		CpXC	177..>222	CDD:291051	20/44 (45%)
		C2H2 Zn finger	178..198	CDD:275368	8/19 (42%)
		C2H2 Zn finger	206..226	CDD:275368	7/19 (37%)
		SIR2	<221..>273	CDD:294129	16/51 (31%)
		C2H2 Zn finger	234..254	CDD:275368	5/19 (26%)
		zf-H2C2_2	246..271	CDD:290200	11/24 (46%)
		C2H2 Zn finger	262..282	CDD:275368	10/19 (53%)
		C2H2 Zn finger	290..310	CDD:275368	7/34 (21%)
		zf-H2C2_2	302..327	CDD:290200	10/39 (26%)
		C2H2 Zn finger	318..338	CDD:275368	9/19 (47%)
		zf-H2C2_2	330..354	CDD:290200	8/26 (31%)
		C2H2 Zn finger	346..366	CDD:275368	5/19 (26%)
		zf-H2C2_2	358..383	CDD:290200	8/24 (33%)
		C2H2 Zn finger	374..394	CDD:275368	6/19 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000003
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000