DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment croc and FKH2

DIOPT Version :9

Sequence 1:	NP_524202.1	Gene:	croc / 40374	FlyBaseID:	FBgn0014143	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_014331.3	Gene:	FKH2 / 855656	SGDID:	S000005012	Length:	862	Species:	Saccharomyces cerevisiae

Alignment Length:	459	Identity:	109/459 - (23%)
Similarity:	168/459 - (36%)	Gaps:	103/459 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 QTAAGYGSASAVAAASSASAAAAAHYAYDQYSRYPYSASAYGLGAPHQNKEIVKPPYSYIALIAM 81
            |.|:..|..:.:.||:...       :|...:.|| .|..:.....|.....||||:||..:|..
Yeast   295 QAASPQGPPNTIIAANFVD-------SYKSSNAYP-QALDFTSDLSHDENRNVKPPHSYATMITQ 351

  Fly    82 AIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKVARDDKKPGKGSYWTL 146
            ||.::.:..::|..||:||...:.|||..|.|||||||||||||:.|.||.|...:||||..|.:
Yeast   352 AILSSPEGVISLADIYKYISSNYAYYRFAKSGWQNSIRHNLSLNKAFEKVPRRPNEPGKGMKWRI 416

  Fly   147 DPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQAMMNEKLAEMKPLKLMTNGILEAKHMAAH 211
            . :||..    .||.:....|...:.|                           |...|:.:..|
Yeast   417 S-ESYQQ----EFLNKWNTGKVGKIRR---------------------------GSSVARQLQLH 449

  Fly   212 AAHFKKEPLMDLGCLSGKEVSHAAMLNSCHDSLAQM----------NHLAGGGVEHPGFTVDSLM 266
            .|.|...|:         |:.:...||.......|:          |::..|.|:|    |.|..
Yeast   450 MAKFNSLPM---------EMDYRLSLNMAQPPKRQLQSHNVLEPSNNNIIEGFVQH----VPSKG 501

  Fly   267 NVYNPRIHHSAYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQLQRHVAHVAHPL-TPGGQGAGG 330
            |:  |....|..|......:.......|...:...    .|....|::| :|.|: ||..| |..
Yeast   502 NL--PASQQSQPPVSHQNQSQQPPPQEQRQEIQFT----FADTQNRNIA-LARPIKTPQLQ-APN 558

  Fly   331 QSSGHSPTTISTPHGPAHGGWYTPETPPSEPVPHNGQQGTPTHPGHNNNNSSSVLNH-------N 388
            .::..:...:.......|        ||:..:....:|..       ||...|..|.       |
Yeast   559 SNANLNQNNMKEYKESLH--------PPAISISQMNRQSP-------NNALVSFTNACANSKIIN 608

  Fly   389 GVGNGGGGGGGGGGGSSSVLTSSPTSALGFRDMIFEQNQSCQLDTGSPTGSLQSASPPASASVAA 453
            .:.:.........||:...|.:..||:|         :::..|:..:.|.|..|.|.|.:.:..:
Yeast   609 NISDSADKSTNNNGGTKMNLPAISTSSL---------DENGNLEPTTTTSSGNSNSVPQTGTTTS 664

  Fly   454 ASAA 457
            :.||
Yeast   665 SLAA 668

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
croc	NP_524202.1	Forkhead	70..156	CDD:278670	41/85 (48%)
FKH2	NP_014331.3	COG5025	1..610	CDD:227358	95/390 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	97	1.000	Domainoid score	I1615
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	1	1.000	-	-		otm46522
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810