Protein Alignment croc and FOXN1

DIOPT Version :10

• Sequence 1: NP_524202.1
• Gene: croc / 40374
• FlyBaseID: FBgn0014143
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: XP_011523660.1
• Gene: FOXN1 / 8456
• HGNCID: 12765
• Length: 649
• Species: Homo sapiens
• Alignment Length: 524
• Identity: 138/524 - (26%)
• Similarity: 184/524 - (35%)
• Gaps: 173/524 - (33%)

  Fly     2 HTLFSDQNSFTRHYAQTAAGYGSASAVAAASSASAAAAAHYAYDQYSRYPYSASAYGLGAPHQNK 66
            |...|.|..|  |  |.:.|.||.......||       ||   ||.|....||..|    || .
Human   223 HMYCSSQPPF--H--QYSPGGGSYPIPYLGSS-------HY---QYQRMAPQASTDG----HQ-P 268

  Fly    67 EIVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKV 131
            ...||.|||..||.||::|:....:.::.||.::.|.|||::....||:||:|||||||:||.||
Human   269 LFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKV 333

  Fly   132 ARDDKKPG----KGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQAMMNEKLAEM 192
               :.|.|    ||..|.|:|                  .|.|.|:|:.:..||:..:..:.:..
Human   334 ---ENKSGSSSRKGCLWALNP------------------AKIDKMQEELQKWKRKDPIAVRKSMA 377

  Fly   193 KPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGC----LSG----KEVSHAAMLNSCHDSLAQMNH 249
            ||.:|  :.::..|.....:      ||  |||    |||    :.::..|.|:....||    |
Human   378 KPEEL--DSLIGDKREKLGS------PL--LGCPPPGLSGSGPIRPLAPPAGLSPPLHSL----H 428

  Fly   250 LAGGGVEHPGFTVDSLMNVYNPRIHHSAYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQLQRHV 314
            .|.|.:.......|.||. :.|..:...| .||: ..||.....|
Human   429 PAPGPIPGKNPLQDLLMG-HTPSCYGQTY-LHLS-PGLAPPGPPQ-------------------- 470

  Fly   315 AHVAHPLTPGGQGAGGQSSGH-----SPTTISTPHGPAHGGWYTPETPPS-------EPVPHNGQ 367
                 ||.|       |..||     .|.|......|||       ||||       ||.|....
Human   471 -----PLFP-------QPDGHLELRAQPGTPQDSPLPAH-------TPPSHSAKLLAEPSPARTM 516

  Fly   368 QGTPTHPGHNNNNSSSVLNHNGVGNGGGGGGGGGGGSSSVLTSSPT-SALGFRDMIFEQ--NQSC 429
            ..|....|....:..::                          :|: :...|:..::||  :.|.
Human   517 HDTLLPDGDLGTDLDAI--------------------------NPSLTDFDFQGNLWEQLKDDSL 555

  Fly   430 QLD-----TGSPTGSLQ-------SASPPASASVAAASAAAAAAVISSHHHHHHHHAALSGNLGQ 482
            .||     |.|||.|..       ...||........|.|...|            |..||..|.
Human   556 ALDPLVLVTSSPTSSSMPPPQPPPHCFPPGPCLTETGSGAGDLA------------APGSGGSGA 608

  Fly   483 LGQL 486
            ||.|
Human   609 LGDL 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
croc	NP_524202.1	FH_FOX	69..159	CDD:469596	38/93 (41%)
FOXN1	XP_011523660.1	FH_FOXN1	271..367	CDD:410830	43/116 (37%)