DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment croc and foxj3

DIOPT Version :9

Sequence 1:NP_524202.1 Gene:croc / 40374 FlyBaseID:FBgn0014143 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_001313317.1 Gene:foxj3 / 797147 ZFINID:ZDB-GENE-101005-1 Length:596 Species:Danio rerio


Alignment Length:513 Identity:126/513 - (24%)
Similarity:175/513 - (34%) Gaps:203/513 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 SAYGLGAP-----------------HQNKEIVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIME 102
            :|:|.|.|                 .|:|: .||||||.:||..||.::..||:||:.|||:|.:
Zfish    31 NAHGPGMPKKSALLDPNTTLDQEEVQQHKD-GKPPYSYASLITFAINSSPKKKMTLSEIYQWICD 94

  Fly   103 RFPYYRDNKQGWQNSIRHNLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFK 167
            .|||||:...||:||||||||||:||:||.|....|||||||.:|.:                  
Zfish    95 NFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTN------------------ 141

  Fly   168 KKDVMREKEEAIKRQAMMNEKLAEMKPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGCLSGKEVS 232
                  .||:.:..:.                                ||.|      .||:..|
Zfish   142 ------PKEDTLPTRP--------------------------------KKRP------RSGERAS 162

  Fly   233 HAAMLNSCHDSLAQMNHLAGGGVEHPGFTVDSLMN---VYNPRIHHSAYP-----YHLNEDNLAT 289
            ....|.|  |:|. |:.:..|... |...::::.|   :|||....|..|     ..|::.:||:
Zfish   163 TPYSLES--DNLG-MDCIISGSAS-PTLAINTVTNKVALYNPDQDGSDSPRSSLNNSLSDQSLAS 223

  Fly   290 VASSQMHHVH-------HAAAAHHAQQLQRHVAHVAHPLTPGGQ--------------------- 326
            |..:.:..||       |..:...:..||:         .|..|                     
Zfish   224 VNLNSVGSVHSYTPVTSHPESVSQSMSLQQ---------APQAQYSIPDRDKQLLFSEFEDLSAS 279

  Fly   327 -------------------GAGGQSSGHSPTTISTPHGPAHGGWYTPETPPSEPVPHNGQQGTPT 372
                               |...:||..:.|:.|..|.|:                        :
Zfish   280 FRSLYKTVFEQSYNQQSLMGLPSESSQQTHTSCSYQHSPS------------------------S 320

  Fly   373 HPGHNNNNSSSVLNHNGVGNGGGGGGGGGGGSSSVLTSSPTSALGFRDMIFEQNQSCQLDTGSPT 437
            || |||.||.:..:.|.:.|         .||...|:..|.||                 ..||.
Zfish   321 HP-HNNQNSITNSHPNNIPN---------NGSQVPLSHPPHSA-----------------HNSPH 358

  Fly   438 GSLQSASPPASASVAAASAAAAAAVISSHH--HHHHHHAALSGNLGQLGQL--SNLSH 491
            |...|...|.|.....|.:..........|  |..|.|.|...:..|..|.  .||||
Zfish   359 GQHLSQHGPHSQHPHTAHSQHPQHSQHPQHSQHSQHGHQAHGQHTAQQQQQQHQNLSH 416

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crocNP_524202.1 Forkhead 70..156 CDD:278670 48/85 (56%)
foxj3NP_001313317.1 Forkhead 62..139 CDD:278670 47/76 (62%)
SelP_N <327..394 CDD:282453 19/92 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.820

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