DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment croc and Foxb1

DIOPT Version :9

Sequence 1:	NP_524202.1	Gene:	croc / 40374	FlyBaseID:	FBgn0014143	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_071773.2	Gene:	Foxb1 / 64290	MGIID:	1927549	Length:	325	Species:	Mus musculus

Alignment Length:	436	Identity:	124/436 - (28%)
Similarity:	175/436 - (40%)	Gaps:	162/436 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 KPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKVARD 134
            |||||||:|.|||||::.:|.:.|:.||::||:||||||:|.|.||||:|||||.|:||:|:.|.
Mouse    13 KPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRR 77

  Fly   135 DKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQAMMNEKLAEMKPLK--- 196
            ..:|||||:|.|.|...:||:||||||||:|||               .:.::.||..||..
Mouse    78 PDQPGKGSFWALHPSCGDMFENGSFLRRRKRFK---------------VLKSDHLAPSKPADAAQ 127

  Fly   197 -LMTNGILEAKHMAAHAAHFKKEPLMDLGCLSGKEVSHAAMLNSCHDSLAQMNHLAG----GGVE 256
             |.....|....:||...|..:.|              ||..|           |.|    .|.:
Mouse   128 YLQQQAKLRLSALAASGTHLPQMP--------------AAAYN-----------LGGVAQPSGFK 167

  Fly   257 HPGFTVDSLM------------NVYNPRIHHSAYPYHLNEDNLATVASS---QMHHVHHAAAAHH 306
            || |.:::::            :...|  ..:|||.   .:.|.|:.||   ...||:.:|.
Mouse   168 HP-FAIENIIAREYKMPGGLAFSAMQP--VPAAYPL---PNQLTTMGSSLGTGWPHVYGSAG--- 223

  Fly   307 AQQLQRHVAHVAHP--LTPGGQGAGG-------QSSGHSPTTISTPHGPAHGGWYTPETPPS--- 359
                   :...|.|  :|.|...|.|       .::|.:...|..|..|      ||...|:
Mouse   224 -------MIDSATPISMTSGDYSAYGVPLKPLCHAAGQTLPAIPVPIKP------TPAAVPALPA 275

  Fly   360 --EPVPHNGQQGTPTHPGHNNNNSSSVLNHNGVGNGGGGGGGGGGGSSSVLTSSPTSALGFRDMI 422
              .|:|                                          ::|::||.|.
Mouse   276 LPAPIP------------------------------------------TLLSNSPPSL------- 291

  Fly   423 FEQNQSCQLDTGSPTGS--LQSASPPASASVAAASAAAAAAVISSH 466
                        |||.|  ..|.|.||:.|....|.|:|...::.|
Mouse   292 ------------SPTSSQTATSQSSPATPSETLTSPASALHSVAVH 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
croc	NP_524202.1	Forkhead	70..156	CDD:278670	51/85 (60%)
Foxb1	NP_071773.2	FH	13..101	CDD:214627	52/87 (60%)
Foxb1	NP_071773.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	284..325		16/59 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910