Protein Alignment croc and Foxo4

DIOPT Version :10

• Sequence 1: NP_524202.1
• Gene: croc / 40374
• FlyBaseID: FBgn0014143
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_061259.1
• Gene: Foxo4 / 54601
• MGIID: 1891915
• Length: 505
• Species: Mus musculus
• Alignment Length: 243
• Identity: 69/243 - (28%)
• Similarity: 111/243 - (45%)
• Gaps: 70/243 - (28%)

  Fly    74 SYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRD-----NKQGWQNSIRHNLSLNECFVKVAR 133
            ||..||:.||::|.:|::||..||::::...||::|     :..||:|||||||||:..|:||
Mouse   105 SYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKV-- 167

  Fly   134 DDKKPGKGSYWTLDPD-----------SYNMFDNGSFLRRRRR--FKKKDVM------------- 172
            .::..||.|:|.|:||           :.:|..:...||.|.:  .||..|:
Mouse   168 HNEATGKSSWWMLNPDGGKGGKAPRRRAASMDSSSKLLRGRSKGPKKKPSVLPAPPEGATPRSPL 232

  Fly   173 ------------REKEEA----------IKRQAMMNEKLAEMKPLKLMTNGILEAKHMAAHAAHF 215
                        |.:|||          ....:.::.:|:.|:|    .:.:|..:.|.|.|:.:
Mouse   233 GHFAKWSSSPCPRNREEADVWTTFRPRSSSNASTVSTRLSPMRP----ESEVLAEEEMPASASSY 293

  Fly   216 K--KEPLM--DLGCLSGKEVSHAAMLNSCHDSLAQMNHLAGGGVEHPG 259
            .  ..|.:  ||..|.|..      |.|.| ||...:.|:|..::|||
Mouse   294 AGGVPPTLSEDLELLDGLN------LASPH-SLLSRSGLSGFSLQHPG 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
croc	NP_524202.1	FH_FOX	69..159	CDD:469596	37/100 (37%)
Foxo4	NP_061259.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..66
		Required for interaction with FOXK1. /evidence=ECO:0000269|PubMed:22956541	97..215		40/111 (36%)
		FH_FOXO4	98..183	CDD:410836	34/79 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	175..244		12/68 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..276		2/18 (11%)
		FOXO_KIX_bdg	<359..399	CDD:465228
		FOXO-TAD	466..503	CDD:435506