DRSC/TRiP Functional Genomics Resources

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Protein Alignment croc and FOXB2

DIOPT Version :9

Sequence 1:NP_524202.1 Gene:croc / 40374 FlyBaseID:FBgn0014143 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_001013757.1 Gene:FOXB2 / 442425 HGNCID:23315 Length:432 Species:Homo sapiens


Alignment Length:466 Identity:137/466 - (29%)
Similarity:176/466 - (37%) Gaps:198/466 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 KPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKVARD 134
            |||||||:|.|||||::|:|.:.|:.||::|||||||||::.|.||||:|||||.|:||:|:.|.
Human    13 KPPYSYISLTAMAIQHSAEKMLPLSDIYKFIMERFPYYREHTQRWQNSLRHNLSFNDCFIKIPRR 77

  Fly   135 DKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQAMMNEKLAEMKPLKLMT 199
            ..:|||||:|.|.||..:||:||||||||:|||                                
Human    78 PDQPGKGSFWALHPDCGDMFENGSFLRRRKRFK-------------------------------- 110

  Fly   200 NGILEAKHMAAHAAHFKKEPLMDLGCLSGKEVSHAAMLNSCHDSLAQMNHLAG-GGVEHPGFTVD 263
              :|.|.|...||...|..|        |                      || ||..||     
Human   111 --VLRADHTHLHAGSTKSAP--------G----------------------AGPGGHLHP----- 138

  Fly   264 SLMNVYNPRIHHSAYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQ-----------LQRHVAHV 317
                      ||..:|:|              ||.|||||.||...           ...|:.|.
Human   139 ----------HHHHHPHH--------------HHHHHAAAHHHHHHHPPQPPPPPPPPPPHMVHY 179

  Fly   318 AHPLTPGGQGAGGQSSGHSPTTISTPHGPAHGGWYTPETPPSEPVPHNGQQGTPTHPGHNNNNSS 382
            .|...|                 :.|..|.|    .|..||.:| |...|...|:||| ....::
Human   180 FHQQPP-----------------TAPQPPPH----LPSQPPQQP-PQQSQPQQPSHPG-KMQEAA 221

  Fly   383 SVLNHNGVGNGGGGGGGGGGGSSSVLTSSPTSALGFRDMIFEQNQSCQLDTGSPTGSLQSASPPA 447
            :|                    ::...::..:|:|                  ..|.| |..||.
Human   222 AV--------------------AAAAAAAAAAAVG------------------SVGRL-SQFPPY 247

  Fly   448 SASVAAASAAAAAAVISSHHH--------------------------HHHHHAALSGNLGQLGQL 486
            ....|||:||||||..|...|                          .||....:.|.||.:   
Human   248 GLGSAAAAAAAAAASTSGFKHPFAIENIIGRDYKGVLQAGGLPLASVMHHLGYPVPGQLGNV--- 309

  Fly   487 SNLSHYRPHVG 497
              :|...||||
Human   310 --VSSVWPHVG 318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crocNP_524202.1 Forkhead 70..156 CDD:278670 53/85 (62%)
FOXB2NP_001013757.1 FH 13..101 CDD:214627 54/87 (62%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 118..220 41/183 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 413..432
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.910

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