DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment croc and foxi1

DIOPT Version :9

Sequence 1:	NP_524202.1	Gene:	croc / 40374	FlyBaseID:	FBgn0014143	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_988949.1	Gene:	foxi1 / 394546	XenbaseID:	XB-GENE-494125	Length:	373	Species:	Xenopus tropicalis

Alignment Length:	397	Identity:	126/397 - (31%)
Similarity:	175/397 - (44%)	Gaps:	91/397 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 NSFTRHYAQTAAGY--GSASAVAAASSASAAAAAHYAYDQYS-RYPYSASAYGLGA--------P 62
            |..|..|:.||..|  .:..::........:..:|:....|. :.....:.:|||.        |
Frog    49 NFETADYSTTANPYLWLNGPSITPPPYLPGSNTSHFMPQSYGMQRQLLPNMHGLGGSDLGWLPIP 113

  Fly    63 HQNK--EIVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLN 125
            .|.:  ::|:|||||.|||||||..|.||::||:.||||:.:.||:|..:|.|||||||||||||
Frog   114 SQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLN 178

  Fly   126 ECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQAMMNEKLA 190
            :||.||.||:..||||:||||||:...|||||:|.|:|:|  |.||            ..|.:::
Frog   179 DCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKR--KSDV------------SPNGQIS 229

  Fly   191 EMKPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGCLSGKEVSHAAMLNSCHDSLAQMNHLAGGGV 255
            ..||                     :..||.:    |.|...|       ||.|         |.
Frog   230 SDKP---------------------EGSPLNE----SPKNGEH-------HDML---------GN 253

  Fly   256 EHPGFTVDSLMNVYNPRIHHSAYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQLQRHVAHVAHP 320
            ..|| |.||......|   .|..|.      |....||...:|:.|.....:..|    .....|
Frog   254 SSPG-TDDSSEKRSPP---PSITPC------LNNFLSSMTAYVNSANPVSRSVPL----GLTNEP 304

  Fly   321 LTPGGQGAGGQSSGHSPTTISTPHGPAHGGWYTPETPPSEPVPHNG---QQGTPTHPGHNNNNSS 382
            ....||...|.:| ::|.:    :.|:|||.....|..|.|..::.   .|.|| |..:..|.::
Frog   305 SDRMGQNMVGLNS-YTPLS----NMPSHGGSDWSSTISSSPFGYSSSVFNQFTP-HFYNTINANN 363

  Fly   383 SVLNHNG 389
            ::.|..|
Frog   364 TLYNREG 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
croc	NP_524202.1	Forkhead	70..156	CDD:278670	56/85 (66%)
foxi1	NP_988949.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23
		Forkhead	123..208	CDD:365978	55/84 (65%)
		COG5025	124..>308	CDD:227358	93/252 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..274		29/124 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11829
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020