DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment croc and foxk1

DIOPT Version :9

Sequence 1:NP_524202.1 Gene:croc / 40374 FlyBaseID:FBgn0014143 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_956196.1 Gene:foxk1 / 334470 ZFINID:ZDB-GENE-030131-6402 Length:639 Species:Danio rerio


Alignment Length:428 Identity:122/428 - (28%)
Similarity:168/428 - (39%) Gaps:98/428 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 AAHYAYDQYSRYPYSASAYGLGAPHQNKEIVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIMER 103
            ||.||....|.  ....|.|..:|   |:..||||||..||..||.:|.|:::||:|||.:|.:.
Zfish   232 AAEYAAKAVSE--QRTEATGGDSP---KDESKPPYSYAQLIVQAISSAQDRQLTLSGIYAHITKH 291

  Fly   104 FPYYRDNKQGWQNSIRHNLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRR--- 165
            :||||...:|||||||||||||..|:||.|..::|||||:|.:||.|.......:|.:||:|   
Zfish   292 YPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRVDPSSEAKLVEQAFRKRRQRGVS 356

  Fly   166 -FKKKDVMREKEEAIKRQAMMNEKLAEMKPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGCLS-- 227
             |:..            ...::.:.|...|    |:..|.:.|.:.         |....|||  
Zfish   357 CFRTP------------FGPLSSRSAPASP----THSGLLSPHSSG---------LQTPECLSRE 396

  Fly   228 GKEVSHAAMLNSCHDSLAQMNHLAGGGVEHPGFTVDS---LMNV-------------YNPRIHHS 276
            |..|||.....|...|:.:..:....    ||..|.:   :|.|             |.|.|..|
Zfish   397 GSPVSHEHDFGSKLASVPEYRYSQSA----PGSPVSAQPVIMAVPSQSSAAISKPVAYMPSIISS 457

  Fly   277 AYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQLQRHVAHVAHPLTPGGQG---AGGQSSGHSPT 338
            :.            ||.|..||...|.|       ..:..|....|....|   |...|||  |.
Zfish   458 SQ------------ASGQAIHVVQQAPA-------VTMVRVVTTSTSSPNGYILANTSSSG--PG 501

  Fly   339 TISTPHGPAHGGWYTPETPPSEPVPHNGQ---QGTPTHPGHNNNNSSS--VLNHNGVGNGGGGGG 398
            .:   ||...|.        .:.:|..|.   |...:|....|....|  |:..:.:.:......
Zfish   502 DL---HGDPRGA--------LDEMPLVGSRVIQAVGSHIASANRGQQSYTVVQQSAIHHLPVQTI 555

  Fly   399 GGGGGSSSVLTSSPTSALGFRDMIFEQNQSCQLDTGSP 436
            ...|..:..:||.||||....:.:  |..:.|..|..|
Zfish   556 AQNGKHALPVTSIPTSAYALTNPL--QILAAQASTSPP 591

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crocNP_524202.1 Forkhead 70..156 CDD:278670 48/85 (56%)
foxk1NP_956196.1 FHA 23..165 CDD:224630
FHA 68..152 CDD:238017
Forkhead 258..344 CDD:278670 48/85 (56%)
Cyto_heme_lyase 370..>465 CDD:279589 27/123 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
54.820

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