DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment croc and Foxk2

DIOPT Version :9

Sequence 1:	NP_524202.1	Gene:	croc / 40374	FlyBaseID:	FBgn0014143	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	XP_006247952.1	Gene:	Foxk2 / 303753	RGDID:	1305408	Length:	650	Species:	Rattus norvegicus

Alignment Length:	411	Identity:	111/411 - (27%)
Similarity:	150/411 - (36%)	Gaps:	122/411 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GSASAV-AAASSASAAAAAHYAYDQY-----------SRYPYSASAYGLGAPHQNKEIVKPPYSY 75
            |:.||. :..||...|.::.|...:.           |:......|.|..:|   |:..||||||
  Rat   193 GTISAANSCPSSPRGAGSSGYKMGRVIPSDLNLMADNSQPENEKEASGGDSP---KDDSKPPYSY 254

  Fly    76 IALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKVARDDKKPGK 140
            ..||..||..|.||::||||||.:|.:.:||||...:|||||||||||||..|:||.|..::|||
  Rat   255 AQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGK 319

  Fly   141 GSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQAMMNEKLAEMKPLKLMTNGILEA 205
            ||:|.:||.|.:.....:|.:||.|                                   |:
  Rat   320 GSFWRIDPASESKLVEQAFRKRRPR-----------------------------------GV--- 346

  Fly   206 KHMAAHAAHFKKEPLM--DLGCLSGKEV----SHAAMLNSCHDSLAQM-NHLAGGG-----VEHP 258
                         |..  .||.||.:..    :||.:| |.|.|.||. ..|:..|     ...|
  Rat   347 -------------PCFRTPLGPLSSRSAPASPNHAGVL-SAHSSGAQTPESLSREGSPAPLEPEP 397

  Fly   259 GFTVDSLMNVYNPRIHHSAYPYHLNEDNLATVASSQM--------HHVHHAAAAHHAQQLQRHVA 315
            |.:...|..:...|...||....|:...:......|:        :.|........:|.......
  Rat   398 GASQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPPAIKPVTYTVATPVTTPTSQPPVVQTV 462

  Fly   316 HVAHPL-----------------TPGGQGAGGQSSGHSPTTISTPHGPAHGGWYTPETPPSEPVP 363
            ||.|.:                 |..||....|::..:|.|     .|...|.:.......||||
  Rat   463 HVVHQIPAVAVTSVAGLAPANTYTVAGQAVVTQAAVLAPKT-----EPQENGDHREVRVKVEPVP 522

  Fly   364 H-------------NGQQGTP 371
            .             ...||||
  Rat   523 AISPATLGAASRIIQTSQGTP 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
croc	NP_524202.1	Forkhead	70..156	CDD:278670	50/85 (59%)
Foxk2	XP_006247952.1	FHA	41..145	CDD:238017
Foxk2	XP_006247952.1	Forkhead	249..335	CDD:278670	50/85 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820