Protein Alignment croc and FOXB1

DIOPT Version :10

• Sequence 1: NP_524202.1
• Gene: croc / 40374
• FlyBaseID: FBgn0014143
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_036314.2
• Gene: FOXB1 / 27023
• HGNCID: 3799
• Length: 325
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 121/419 - (28%)
• Similarity: 175/419 - (41%)
• Gaps: 128/419 - (30%)

  Fly    70 KPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKVARD 134
            |||||||:|.|||||::.:|.:.|:.||::||:||||||:|.|.||||:|||||.|:||:|:.|.
Human    13 KPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRR 77

  Fly   135 DKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQAMMNEKLAEMKPLK--- 196
            ..:|||||:|.|.|...:||:||||||||:|||               .:.::.||..||..
Human    78 PDQPGKGSFWALHPSCGDMFENGSFLRRRKRFK---------------VLKSDHLAPSKPADAAQ 127

  Fly   197 -LMTNGILEAKHMAAHAAHFKKEPLMDLGCLSGKEVSHAAMLNSCHDSLAQMNHLAG----GGVE 256
             |.....|....:||...|..:.|              ||..|           |.|    .|.:
Human   128 YLQQQAKLRLSALAASGTHLPQMP--------------AAAYN-----------LGGVAQPSGFK 167

  Fly   257 HPGFTVDSLM------------NVYNPRIHHSAYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQ 309
            || |.:::::            :...|  ..:|||.   .:.|.|:.||
Human   168 HP-FAIENIIAREYKMPGGLAFSAMQP--VPAAYPL---PNQLTTMGSS---------------- 210

  Fly   310 LQRHVAHVAHPLTPGGQGAGGQSSGHSPTTISTPHGPAHGGWYTPETPPSEPVPHNGQQGTPTHP 374
            |.....||        .|:.|.....:|.::::       |.|:....|.:|:.|...|..|..|
Human   211 LGTGWPHV--------YGSAGMIDSATPISMAS-------GDYSAYGVPLKPLCHAAGQTLPAIP 260

  Fly   375 GHNNNNSSSVLNHNGVGNGGGGGGGGGGGSSSVLTSSPTSALGFRDMIFEQNQSCQLDTGSPTGS 439
            .......::|.....:          .....::|::||.|.                   |||.|
Human   261 VPIKPTPAAVPALPAL----------PAPIPTLLSNSPPSL-------------------SPTSS 296

  Fly   440 --LQSASPPASASVAAASAAAAAAVISSH 466
              ..|.|.||:.|....|.|:|...::.|
Human   297 QTATSQSSPATPSETLTSPASALHSVAVH 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
croc	NP_524202.1	FH_FOX	69..159	CDD:469596	53/88 (60%)
FOXB1	NP_036314.2	FH_FOXB2	1..110	CDD:410817	60/96 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	284..325		16/59 (27%)