Protein Alignment croc and Foxa2

DIOPT Version :10

• Sequence 1: NP_524202.1
• Gene: croc / 40374
• FlyBaseID: FBgn0014143
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001386014.1
• Gene: Foxa2 / 25099
• RGDID: 2808
• Length: 465
• Species: Rattus norvegicus
• Alignment Length: 384
• Identity: 128/384 - (33%)
• Similarity: 170/384 - (44%)
• Gaps: 90/384 - (23%)

  Fly    20 AGYGSASAVAAASSASAAAAA------HYAYDQYSRYPYSASAYGLGAPHQNKEIV--------- 69
            ||....:...|..|.||.||.      |.:.........:|.|.|..||:.|...:
  Rat    84 AGMSPGAGAMAGMSGSAGAAGVAGMGPHLSPSLSPLGGQAAGAMGGLAPYANMNSMSPMYGQAGL 148

  Fly    70 ----------------KPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSI 118
                            |||||||:||.||||.:.:|.:||:.|||:||:.||:||.|:|.|||||
  Rat   149 SRARDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSI 213

  Fly   119 RHNLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQA 183
            ||:||.|:||:||.|...||||||:|||.|||.|||:||.:|||::|||     .||:.|:|..|
  Rat   214 RHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFK-----CEKQLALKEAA 273

  Fly   184 ---------------MMNEKLAEMKPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGCLSGKEVSH 233
                           ....:|.|.......|....|:.|.:|......|.     |.||..:.:.
  Rat   274 GAGSGGGKKTAPGTQASQVQLGEAAGSASETPAGTESPHSSASPCQEHKR-----GGLSELKGTP 333

  Fly   234 AAMLNSCH--DSLAQMNHLAGGGV---EHPGFTVDSLMNVYNPRIHHSAYPYHLNEDNLATVASS 293
            |:.|:...  .|..|....|...:   .|||...::.:   .|. ||.|:.:..:.:||  ::|.
  Rat   334 ASALSPPEPAPSPGQQQQAAAHLLVPPHHPGLPPEAHL---KPE-HHYAFNHPFSINNL--MSSE 392

  Fly   294 QMHHVHHAAAAHHAQ------QLQRHVAHVAHPLTPGGQGAGGQSSGHSPTTISTPHGP 346
            |.||..|    ||.|      :....|.|.     |||.|        ||...|...||
  Rat   393 QQHHHSH----HHHQPHKMDLKTYEQVMHY-----PGGYG--------SPMPGSLAMGP 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
croc	NP_524202.1	FH_FOX	69..159	CDD:469596	59/114 (52%)
Foxa2	NP_001386014.1	Forkhead_N	23..164	CDD:369872	15/79 (19%)
		FH_FOXA2	163..264	CDD:410813	65/105 (62%)
		COG5025	<164..380	CDD:227358	92/229 (40%)
		HNF_C	380..454	CDD:430552	21/74 (28%)