DRSC/TRiP Functional Genomics Resources

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Protein Alignment croc and Foxg1

DIOPT Version :9

Sequence 1:NP_524202.1 Gene:croc / 40374 FlyBaseID:FBgn0014143 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_036692.1 Gene:Foxg1 / 24370 RGDID:2619 Length:480 Species:Rattus norvegicus


Alignment Length:357 Identity:115/357 - (32%)
Similarity:154/357 - (43%) Gaps:84/357 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 QNKEIVKPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECF 128
            :|.:..|||:||.|||.|||:.:.:|::||||||::||:.|||||:||||||||||||||||:||
  Rat   166 KNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCF 230

  Fly   129 VKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQAMMNEKLAEMK 193
            |||.|....||||:||.|||.|.::|..|:..:.||                |......|||..:
  Rat   231 VKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRR----------------RSTTSRAKLAFKR 279

  Fly   194 PLKLMTNGILEAKHMAAHAAHFKKEPLMDL------GCLSGKEVSHAAMLNSC-HDSLAQMNHLA 251
            ..:|.:.|:.....  |.:.::...|.:.|      ..||....:.|...:.. :.|:...|.| 
  Rat   280 GARLTSTGLTFMDR--AGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQNSL- 341

  Fly   252 GGGVEHP-----GFTVDSLMNVYNPRIHHSAYPYHLNEDNLA-------TVASSQMHHVHHAAAA 304
              |..|.     |.:||.|:|...|...|     ||....||       :|..|..:.::..:..
  Rat   342 --GNNHSFSTANGLSVDRLVNGEIPYATH-----HLTAAALAASVPCGLSVPCSGTYSLNPCSVN 399

  Fly   305 HHAQQLQRHVAHVAHP----LTPGGQGAGGQSSGHSPTTISTPHGPAHGGWYTPETPPSEPVPHN 365
            ..|.|......||.||    .|.....|...||..||              ..|.|.|.|.:   
  Rat   400 LLAGQTSYFFPHVPHPSMTSQTSTSMSARAASSSTSP--------------QAPSTLPCESL--- 447

  Fly   366 GQQGTPTHPG--------------HNNNNSSS 383
                .|:.|.              |.|..|||
  Rat   448 ----RPSLPSFTTGLSGGLSDYFTHQNQGSSS 475

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
crocNP_524202.1 Forkhead 70..156 CDD:278670 58/85 (68%)
Foxg1NP_036692.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 31..172 1/5 (20%)
FH_FOXG 172..250 CDD:410795 54/77 (70%)
COG5025 <175..>347 CDD:227358 75/192 (39%)
Required for interaction with TLE6. /evidence=ECO:0000250|UniProtKB:Q60987 240..335 26/112 (23%)
Interaction with KDM5B. /evidence=ECO:0000250 374..397 4/22 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 418..446 9/41 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
54.820

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