DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment croc and Foxj3

DIOPT Version :9

Sequence 1:	NP_524202.1	Gene:	croc / 40374	FlyBaseID:	FBgn0014143	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_001344106.1	Gene:	Foxj3 / 230700	MGIID:	2443432	Length:	623	Species:	Mus musculus

Alignment Length:	418	Identity:	108/418 - (25%)
Similarity:	165/418 - (39%)	Gaps:	111/418 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 SAYGLGAPHQN-----------KEIV-----KPPYSYIALIAMAIQNAADKKVTLNGIYQYIMER 103
            :|:|.|...:|           :|:.     ||||||.:||..||.::..||:||:.|||:|.:.
Mouse    47 NAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDN 111

  Fly   104 FPYYRDNKQGWQNSIRHNLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDNGSFLRRRRRFKK 168
            |||||:...||:||||||||||:||:||.|....|||||||.:|.:     .....|..|.:.:.
Mouse   112 FPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTN-----PKEDTLPTRPKKRA 171

  Fly   169 KDVMREK------EEAIKRQAMMNEKLAEMKPLKLMTNGILEAKHMAAHAAHFKKEPLMDLGCLS 227
            :.|.|..      .:::..:.:::...:....:..:||                |..|.:.. ..
Mouse   172 RSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTN----------------KVTLYNAD-QD 219

  Fly   228 GKEVSHAAMLNSCHD-SLAQMNHLAGGGV----------------------EHPGFTVDS----- 264
            |.:...:::.||..| |||.:|..:.|.|                      :.|.:.:..
Mouse   220 GSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVSQPLTPQQQQQPQYNLPEREKQL 284

  Fly   265 LMNVYN--------PRIHHSAYPYHLNEDNLATVASSQMHHVHHAAAAHHAQQ----LQRHVAHV 317
            |...||        ..::.|.:...|::..|.::.|......|.:.:..|:..    ...|....
Mouse   285 LFTEYNFEDLSASFRSLYKSVFEQSLSQQGLMSIPSESSQQSHTSCSYQHSPSSTVTSHPHSNQS 349

  Fly   318 AHPLTPGGQGAGGQSS----------GHSPTTISTPHGPAHGGWYTPETP--PSEPVPHNGQ--- 367
            :.|....|..|.|.:|          .|...:..|||.| ||   .|:.|  |..|.||..|
Mouse   350 SLPNNHSGLSATGSNSVAQVSLSHPQMHPQPSPHTPHRP-HG---LPQHPQRPQHPAPHPQQHSQ 410

  Fly   368 ------QGTPTHP--GHNNNNSSSVLNH 387
                  |..|.|.  .|:.|:....|.|
Mouse   411 LQPPHSQHPPPHQHIQHHPNHQHQTLAH 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
croc	NP_524202.1	Forkhead	70..156	CDD:278670	48/85 (56%)
Foxj3	NP_001344106.1	COG5025	<54..347	CDD:227358	79/314 (25%)
		Forkhead	78..155	CDD:365978	47/76 (62%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	143..178		12/39 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	248..275		2/26 (8%)
		PAT1	<311..>434	CDD:370676	29/126 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	316..451		30/127 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820