Protein Alignment croc and FOXD2

DIOPT Version :10

• Sequence 1: NP_524202.1
• Gene: croc / 40374
• FlyBaseID: FBgn0014143
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_004465.3
• Gene: FOXD2 / 2306
• HGNCID: 3803
• Length: 495
• Species: Homo sapiens
• Alignment Length: 519
• Identity: 156/519 - (30%)
• Similarity: 195/519 - (37%)
• Gaps: 165/519 - (31%)

  Fly    17 QTAAGYGSASAVAAASSASAAAAAHYAYDQYSRYPYSASAYGLGAP---------HQNKEIVKPP 72
            :.:.|.......|.||..:||||.       |..|.:|:|.|...|         .....:||||
Human    72 EESGGCSDGEPRALASRGAAAAAG-------SPGPGAAAARGAAGPGPGPPSGGAATRSPLVKPP 129

  Fly    73 YSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKVARDDKK 137
            |||||||.|||..:..|::||:.|.::|..||||||:....||||||||||||:||||:.|:...
Human   130 YSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGN 194

  Fly   138 PGKGSYWTLDPDSYNMFDNGSFLRRRRRFKKKDVMREKEEAIKRQAMMNEKLAEMKPLKLMTNGI 202
            ||||:||||||:|.:|||||||||||:|||::.
Human   195 PGKGNYWTLDPESADMFDNGSFLRRRKRFKRQP-------------------------------- 227

  Fly   203 LEAKHMAAHAAHFKKEPLMDLGCLSGKEVSHAAMLNSCHDSLAQMNHLAGG-------GVEHPGF 260
            |...|...|                    .|..:|            |.||       |...|||
Human   228 LPPPHPHPH--------------------PHPELL------------LRGGAAAAGDPGAFLPGF 260

  Fly   261 TVDSLMNVYNPRIHHSAYPYHLNEDNLATVA--------SSQMH-HVH----HAAAAHHAQQLQR 312
            ..            :.||.|..   .||..|        :...| |.|    .||||....||..
Human   261 AA------------YGAYGYGY---GLALPAYGAPPPGPAPHPHPHPHAFAFAAAAAAAPCQLSV 310

  Fly   313 HVAHVAHPLTPGGQGA-----GGQSSGHSPTTISTPHGPAHGG--------------WYTPETPP 358
            .....|.| .||...|     .|.:...:|.:.|.| ||...|              :|.....|
Human   311 PPGRAAAP-PPGPPTASVFAGAGSAPAPAPASGSGP-GPGPAGLPAFLGAELGCAKAFYAASLSP 373

  Fly   359 SEPVPHNG-QQGTPTHPGHNNNNSSSVLNHNGVGNGGGGGGGGGGGSSSVLTSSPTSALGFRDMI 422
                |..| ..|.||           .|...|:....|||.||||..:.   ..|:.::   |.|
Human   374 ----PAAGTAAGLPT-----------ALLRQGLKTDAGGGAGGGGAGAG---QRPSFSI---DHI 417

  Fly   423 FEQNQSCQLDTGSPTGS-----LQSASPPASASVAAASAAAAAAVISSHHHHHHHHAAL--SGN 479
            ...........|:..||     ..:|.|...|.|.|...|.|.|.::.|....|...||  ||:
Human   418 MGHGGGGAAPPGAGEGSPGPPFAAAAGPGGQAQVLAMLTAPALAPVAGHIRLSHPGDALLSSGS 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
croc	NP_524202.1	FH_FOX	69..159	CDD:469596	58/89 (65%)
FOXD2	NP_004465.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	14..122		14/56 (25%)
		FH_FOXD1_D2-like	127..225	CDD:410820	65/97 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	312..347		9/36 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..444		12/52 (23%)